SCHEMBL4594840

SCHEMBL4594840

OCCCCCCOc1ccc2cc(Br)ccc2c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.47
LSS P48449 1/20 0.45
PDE2A O00408 1/20 0.45
PDE3B Q13370 1/20 0.45
PDE3A Q14432 1/20 0.45
P2RY12 Q9H244 1/20 0.45
NPSR1 Q6W5P4 1/20 0.43
SLC6A2 P23975 3/20 0.43
SLC6A4 P31645 3/20 0.43
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PDK2 Q15119 2/20 0.42
NCEH1 Q6PIU2 1/20 0.41
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM1A O60341 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30754663 1.00 HDAC1 (0.47) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL9805741 1.00 HDAC1 (0.47) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL30457219 1.00 HDAC1 (0.47) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL30754667 1.00 HDAC1 (0.47) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL24961871 1.00 HDAC1 (0.47) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL24962598 1.00 HDAC1 (0.47) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL30457019 0.93 SLC6A2 (0.48) HDAC1PDE2APDE3BPDE3AP2RY12
SCHEMBL6027823 0.93 SLC6A2 (0.48) HDAC1PDE2APDE3BPDE3AP2RY12
SCHEMBL7688296 0.91 NPC1 (0.43) HDAC1LSSPDE2APDE3BPDE3A
SCHEMBL7689815 0.89 HDAC1 (0.42) HDAC1LSSPDE2APDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085241-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2026-03-26 US disclosed
US-12534670-B2 Liquid crystal compounds Rolic Technologies AG (CH) 2026-01-27 US disclosed
EP-4594446-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2025-08-06 EP disclosed
US-20250066666-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2025-02-27 US disclosed
EP-4444822-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2024-10-16 EP disclosed
CN-118318024-A Liquid crystal compound 罗利克技术有限公司 2024-07-09 CN disclosed
WO-2024068311-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2024-04-04 WO disclosed
CN-117500898-A Liquid crystal compound 罗利克技术有限公司 2024-02-02 CN disclosed
WO-2023104545-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2023-06-15 WO disclosed
WO-2023006599-A1 LIQUID CRYSTAL COMPOUNDS Rolic Technologies AG (CH) 2023-02-02 WO disclosed
EP-1187802-B1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2008-01-02 EP disclosed
US-6746729-B1 COMPONENTS OF POLYMERIZABLE LIQUID CRYSTALLINE MIXTURES IN PRODUCTION OF ORIENTATED LIQUID CRYSTALLINE POLYMER NETWORKS ROLIC AG (CH) 2004-06-08 US disclosed
CN-1137126-C Silane derivatives incorporating photoreactive groups 罗利克公司 2004-02-04 CN disclosed
EP-0844248-B1 Crosslinkable, photoactive silane derivatives ROLIC AG (CH) 2002-07-10 EP disclosed
EP-1187802-A1 LIQUID CRYSTAL COMPOUNDS Rolic AG (CH) 2002-03-20 EP disclosed
WO-2000063154-A1 LIQUID CRYSTAL COMPOUNDS ROLIC AG (CH) 2000-10-26 WO disclosed
EP-1046631-A1 Liquid crystalline compounds Rolic AG (CH) 2000-10-25 EP disclosed
US-5965761-A CROSSLINKABLE SILANE DERIVAATIVES HAVING A 3-ARYLACRYLIC ACID OR-ACRYLAMIDE GROUP FOR ORIENTING LAYER AND FOR NONSTRUCTURED AND STRUCTURED OPTICAL ELEMENTS AND MULTILAYER SYSTEMS; PHOTOSTABILITY; CONTRAST; RESOLUTION ROLIC AG (CH) 1999-10-12 US disclosed
EP-0844248-A2 Crosslinkable, photoactive silane derivatives Rolic AG (CH) 1998-05-27 EP disclosed
CN-1181383-A Silane derivatives incorporating photoreactive groups ROLIC AG (CH) 1998-05-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085241-A1 LIQUID CRYSTAL COMPOUNDS SCO2, CCRL2, OGFRL1 HDAC1 2797/4885LSS 723/4885PDE2A 4570/4885
US-12534670-B2 Liquid crystal compounds SCO2, LBR, C1R HDAC1 4042/4885LSS 204/4885PDE2A 4524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.