Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805741 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL30754663 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL30754667 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL24961871 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL30457219 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL24962598 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL4594840 | 0.89 | HDAC1 (0.47) | HDAC1LSSPDE2APDE3BPDE3A | |
| SCHEMBL6027823 | 0.82 | SLC6A2 (0.48) | HDAC1PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL30457019 | 0.82 | SLC6A2 (0.48) | HDAC1PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL7692001 | 0.81 | NPC1 (0.37) | HDAC1LMNASMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |