Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 8/20 | 0.50 |
| ▸ | GSK3B | P49841 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153669 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL28792111 | 0.89 | GSK3A (0.56) | GSK3AGSK3BMEN1KMT2AGAA | |
| Acetic Acid SCHEMBL9131138 | 0.82 | GSK3A (0.64) | GSK3AGSK3BMEN1KMT2AGAA | |
| Isothiocyanate SCHEMBL28928634 | 0.78 | GSK3A (0.46) | GSK3AGSK3BMEN1KMT2AGAA | |
| Morpholine SCHEMBL4579822 | 0.76 | GSK3A (0.44) | GSK3AGSK3BMEN1KMT2AGAA | |
| 3-Methyl-Rhodanine SCHEMBL25418661 | 0.76 | GSK3A (0.80) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL3138532 | 0.76 | GSK3A (0.56) | GSK3AGSK3BMEN1KMT2AGAA | |
| Thiazolidine SCHEMBL27361507 | 0.74 | GSK3A (0.43) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL3062340 | 0.74 | GSK3A (0.62) | GSK3AGSK3BMEN1KMT2AGAA | |
| SCHEMBL2788487 | 0.73 | MEN1 (0.59) | GSK3AGSK3BMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497650-A4 | A METHOD FOR DETECTING LYSOSOMAL STORAGE DISEASES | SEIKAGAKU KOGYO CO LTD (JP) | 2008-04-02 | — | — | EP | disclosed |
| EP-1497650-A2 | A METHOD FOR DETECTING LYSOSOMAL STORAGE DISEASES | SEIKAGAKU CORPORATION (JP) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003092601-A2 | A METHOD FOR DETECTING LYSOSOMAL STORAGE DISEASES | SEIKAGAKU CORPORATION (JP) | 2003-11-13 | — | — | WO | disclosed |
| WO-1993015406-A1 | METHODS AND APPARATUS FOR ASSAY OF SULPHATED POLYSACCHARIDES | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDECINE (GB) | 1993-08-05 | — | — | WO | disclosed |