Morpholine

Morpholine

SCHEMBL4579822

C1COCCN1.CCN1C(=O)CSC1=S

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 8/20 0.44
GSK3B P49841 8/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
ALDH1A1 P00352 6/20 0.43
RECQL P46063 3/20 0.43
GAA P10253 5/20 0.38
HTT P42858 3/20 0.37
MAPT P10636 2/20 0.37
THRB P10828 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
POLB P06746 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
MAPK1 P28482 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PAX8 Q06710 1/20 0.36
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153669 0.83
Ammonia Solution, Strong SCHEMBL28792111 0.82 GSK3A (0.56) GSK3AGSK3BMEN1KMT2AALDH1A1
Isothiocyanate SCHEMBL4594925 0.76 GSK3A (0.50) GSK3AGSK3BMEN1KMT2AALDH1A1
Acetic Acid SCHEMBL9131138 0.76 GSK3A (0.64) GSK3AGSK3BMEN1KMT2AALDH1A1
SCHEMBL4579816 0.70 GSK3A (0.49) GSK3AGSK3BMEN1KMT2AALDH1A1
SCHEMBL3138532 0.70 GSK3A (0.56) GSK3AGSK3BMEN1KMT2AALDH1A1
SCHEMBL3062340 0.68 GSK3A (0.62) GSK3AGSK3BMEN1KMT2AALDH1A1
SCHEMBL4655348 0.68 MEN1 (0.42) GSK3AGSK3BMEN1KMT2AALDH1A1
SCHEMBL2788487 0.67 MEN1 (0.59) GSK3AGSK3BMEN1KMT2AALDH1A1
SCHEMBL3081982 0.67 MEN1 (0.51) GSK3AGSK3BMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435529-B2 Photosensitive composition and image recording method using the same FUJIFILM CORPORATION (JP) 2008-10-14 US disclosed
EP-1445120-B1 Photosensitive lithographic printing plate FUJIFILM CORP (JP) 2007-07-18 EP disclosed
US-20070009831-A1 PLANOGRAPHIC PRINTING PLATE MATERIAL AND IMAGE FORMATION METHOD KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-11 US disclosed
US-20060128823-A1 Radiation curable inkjet recording ink, and method of producing planographic printing plate using same, and ink composition, inkjet recording method, printed material, method of producing a planographic printing plate, and planographic printing plate FUJI PHOTO FILM CO., LTD. 2006-06-15 US disclosed
EP-1657286-A2 Radiation curable ink jet ink, comprising a polymerisation initiation sensitising dye FUJI PHOTO FILM CO., LTD. (JP) 2006-05-17 EP disclosed
US-20060008733-A1 Photosensitive composition and image recording method using the same FUJI PHOTO FILM CO., LTD. 2006-01-12 US disclosed
EP-1615073-A1 Photosensitive composition and image recording method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-01-11 EP disclosed
EP-1445120-A2 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2004-08-11 EP disclosed
US-6468711-B1 TITANOCENE COMPOUNDS AND A CARBONYLTHIAZOLE DYE OR MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 2002-10-22 US disclosed
EP-1048982-B1 Photopolymerizable composition for short wavelenght semiconductor laser exposure, photosensitive composition and method for polymerizing photosensitive composition FUJI PHOTO FILM CO LTD (JP) 2002-10-02 EP disclosed
US-6335144-B1 FOR A LITHOGRAPHIC PRINTING PLATE PRECURSOR CAPABLE OF PLATE-MAKING BY SCANNING EXPOSURE BASED ON DIGITAL SIGNALS, USED IN OPTICAL IMAGE-FORMING, HOLOGRAPHY, AND A COLOR HARD COPY, PRODUCTION OF ELECTRONIC MATERIALS SUCH AS PHOTORESISTS FUJI PHOTO FILM CO., LTD. 2002-01-01 US disclosed
EP-1048982-A1 Photopolymerizable composition for short wavelenght semiconductor laser exposure, photosensitive composition and method for polymerizing photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-0985683-A1 Photosensitive composition and method for manufacturing lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2000-03-15 EP disclosed