Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 13/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308055 | 0.93 | LMNA (0.56) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL1306702 | 0.90 | ALDH1A1 (0.53) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL4594956 | 0.88 | LMNA (0.47) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL3454916 | 0.86 | AVPR1A (0.56) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL1307671 | 0.85 | ALDH1A1 (0.53) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL4204995 | 0.84 | LMNA (0.53) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL1307883 | 0.81 | ALDH1A1 (0.55) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL3456081 | 0.79 | AVPR1A (0.54) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL3455696 | 0.78 | ALDH1A1 (0.51) | LMNAAVPR1AAVPR2ALDH1A1MEN1 | |
| SCHEMBL1308165 | 0.78 | ALDH1A1 (0.56) | LMNAAVPR1AAVPR2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945207-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | Transtech Pharma, Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007051811-A2 | PHARMACEUTICAL USE OF SUBSTITUTED AMIDES | TRANSTECH PHARMA (US) | 2007-05-10 | — | — | WO | disclosed |