Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32674587 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL4247092 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL18211545 | 0.85 | LMNA (0.48) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL9007595 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21853751 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL2065376 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21853762 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21791552 | 0.85 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL4594968 | 0.83 | LMNA (0.50) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL2996166 | 0.81 | LMNA (0.48) | LMNATSHRMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948594-B1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2013-02-27 | — | — | EP | disclosed |
| EP-1948594-A1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007054147-A1 | PROCESS FOR THE SYNTHESIS OF INTERMEDIATES OF CHLORAMPHENICOL OR ITS ANALOGUES | KRKA (SI) | 2007-05-18 | — | — | WO | disclosed |
| EP-1785414-A1 | Process for the synthesis of intermediates of chloramphenicol or its analogues | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2007-05-16 | — | — | EP | disclosed |
| US-3927054-A | Process for producing {62 -phenylserine copper complex | SUMITOMO CHEMICAL CO | 1975-12-16 | — | — | US | disclosed |