Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25588104 | 0.86 | LMNA (0.44) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL1835877 | 0.85 | LMNA (0.46) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL3637756 | 0.85 | LMNA (0.46) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL5013214 | 0.85 | LMNA (0.46) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL25588108 | 0.84 | LMNA (0.42) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL4247092 | 0.82 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21853751 | 0.82 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21791552 | 0.82 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL2065376 | 0.82 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A | |
| SCHEMBL21853762 | 0.82 | LMNA (0.51) | LMNATSHRMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084745-A | Preparation method of florfenicol intermediate D-ester | 和融(河北)药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20230183175-A1 | METHOD FOR PREPARING INTERMEDIATE FOR USE IN SYNTHESIS OF FLORFENICOL AND COMPOUNDS PREPARED THEREBY | HEADING NANJING PHARMTECHNOLOGIES CO LTD (CN) | 2023-06-15 | — | — | US | disclosed |
| US-20230183175-A1 | METHOD FOR PREPARING INTERMEDIATE FOR USE IN SYNTHESIS OF FLORFENICOL AND COMPOUNDS PREPARED THEREBY | HEADING NANJING PHARMTECHNOLOGIES CO LTD (CN) | 2023-06-15 | — | — | US | disclosed |
| WO-2020135000-A1 | PREPARATION METHOD FOR THREE-PHENYL-L-SERINE OR DERIVATIVES THEREOF AND ETHYL ESTER THEREOF | 苏州引航生物科技有限公司 | 2020-07-02 | — | — | WO | disclosed |
| EP-1928820-B1 | A PROCESS FOR PREPARING ESTER OXAZOLIDINE COMPOUNDS AND THEIR CONVERSION TO FLORFENICOL | INTERVET INT BV (NL) | 2014-01-29 | — | — | EP | disclosed |
| US-7786329-B2 | Process for preparing ester oxazolidine compounds and their conversion to Florfenicol | INTERVET INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-1934190-A2 | AN IMPROVED PROCESS FOR PREPARING OXAZOLIDINE PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | Schering-Plough Ltd. (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1934189-A2 | A PROCESS FOR PREPARING OXAZOLIDINE PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | Schering-Plough Ltd. (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1928820-A2 | A PROCESS FOR PREPARING ESTER OXAZOLIDINE COMPOUNDS AND THEIR CONVERSION TO FLORFENICOL | Schering-Plough Ltd. (CH) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007030405-A2 | A PROCESS FOR PREPARING ESTER OXAZOLIDINE COMPOUNDS AND THEIR CONVERSION TO FLORFENICOL | SCHERING-PLOUGH LTD. (CH) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030385-A2 | A PROCESS FOR PREPARING OXAZOLIDINE PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | SCHERING-PLOUGH LTD. (CH) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007030386-A2 | AN IMPROVED PROCESS FOR PREPARING OXAZOLIDINE PROTECTED AMINODIOL COMPOUNDS USEFUL AS INTERMEDIATES TO FLORFENICOL | SCHERING-PLOUGH LTD. (CH) | 2007-03-15 | — | — | WO | disclosed |
| US-20070055080-A1 | Process for preparing ester oxazolidine compounds and their conversion to Florfenicol | SCHERING-PLOUGH ANIMAL HEALTH CORP. | 2007-03-08 | — | — | US | disclosed |
| US-20070055066-A1 | Process for preparing oxazolidine protected aminodiol compounds useful as intermediates to florfenicol | SCHERING-PLOUGH ANIMAL HEALTH CORP | 2007-03-08 | — | — | US | disclosed |
| US-20070055067-A1 | Process for preparing oxazolidine protected aminodiol compounds useful as intermediates to Florfenicol | SCHERING-PLOUGH ANIMAL HEALTH CORP. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055080-A1 | Process for preparing ester oxazolidine compounds and their conversion to Florfenicol | CYP4F8, CYP4F2, CYP2F1 | LMNA 1934/4885TSHR 3720/4885MEN1 1509/4885 |
| US-20070055067-A1 | Process for preparing oxazolidine protected aminodiol compounds useful as intermediates to Florfenicol | DHFR, DPYD, AMPD2 | LMNA 1668/4885TSHR 4433/4885MEN1 1783/4885 |
| US-20070055066-A1 | Process for preparing oxazolidine protected aminodiol compounds useful as intermediates to florfenicol | DHFR, DPYD, AMPD2 | LMNA 1668/4885TSHR 4433/4885MEN1 1783/4885 |
| US-20230183175-A1 | METHOD FOR PREPARING INTERMEDIATE FOR USE IN SYNTHESIS OF FLORFENICOL AND COMPOUNDS PREPARED THEREBY | CYP4F2, CYP4F3, CYP2F1 | LMNA 3718/4885TSHR 4697/4885MEN1 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.