Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | CA6 | P23280 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790769 | 1.00 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169546 | 1.00 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL7338783 | 0.98 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL225031 | 0.98 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL23056654 | 0.94 | PTGS2 (0.59) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL793526 | 0.94 | PTGS2 (0.59) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169544 | 0.94 | PTGS2 (0.59) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9145459 | 0.91 | PTGS2 (0.54) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9144882 | 0.88 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29016897 | 0.86 | DDB1 (0.61) | PTGS2PTGS1OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117417245-A | Method for synthesizing ketoprofen through pyrolytic aromatization reaction | 复旦大学 | 2024-01-19 | — | — | CN | claimed |
| CN-116043244-A | Method for preparing alpha, beta-unsaturated ketone by electrocatalytic oxidation of alcohol | 北京化工大学 | 2023-05-02 | — | — | CN | claimed |
| CN-107365986-B | A kind of chemical tin inorganic agent and the tin plating technique using the chemical tin inorganic agent | 东莞市富默克化工有限公司 | 2019-08-09 | — | — | CN | claimed |
| CN-105969329-B | A kind of hypertonic very poor low fingering noresidue acidifying solution of low permeability reservoir man-made fracture and preparation method thereof | 宁夏朔光石油科技有限公司 | 2019-01-29 | — | — | CN | claimed |
| CN-107365986-A | A kind of tin plating technique of chemical tin inorganic agent and application the chemical tin inorganic agent | 东莞市富默克化工有限公司 | 2017-11-21 | — | — | CN | claimed |
| EP-1152006-A2 | Tetrahydrofluorenyl containing group 4 metallocenes useful as catalysts for the polymerization of olefins, process for their preparation and use of said metallocenes for the polymerization of ofelins | SOLVAY POLYOLEFINS EUROPE - BELGIUM (Société Anonyme) (BE) | 2001-11-07 | — | — | EP | claimed |
| CN-116832869-B | Magnetic nano bimetallic catalyst and preparation method and catalytic application thereof | 河北师范大学 | 2025-05-13 | — | — | CN | disclosed |
| EP-4069366-B1 | ATM KINASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION INC (US) | 2025-03-19 | — | — | EP | disclosed |
| CN-117701516-A | Alkene reductase, enzyme preparation, nucleic acid, expression vector, preparation method and application | 河北工业大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-117417245-A | Method for synthesizing ketoprofen through pyrolytic aromatization reaction | 复旦大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-117417245-A | Method for synthesizing ketoprofen through pyrolytic aromatization reaction | 复旦大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-116832869-A | Magnetic nano bimetallic catalyst and preparation method and catalytic application thereof | 河北师范大学 | 2023-10-03 | — | — | CN | disclosed |
| US-11685734-B2 | ATM kinase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2023-06-27 | — | — | US | disclosed |
| US-5057513-A | Platelet activating factor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0399424-A1 | Thiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-28 | — | — | EP | disclosed |
| EP-0085811-B1 | 2-(PHENYLMETHYLENE)CYCLOALKYLAMINES | THE UPJOHN COMPANY (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4587261-A | FATTENING AGENTS FOR ANIMALS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1986-05-06 | — | — | US | disclosed |
| US-4540690-A | ANALGESICS, ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
| US-4221788-A | 2-(Optionally-substituted)benzylperhydroazepines for analgesia and lowering blood pressure | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-09-09 | — | — | US | disclosed |
| US-4187152-A | Extractive distillation for separating ketones and/or alcohols from phenol and/or cresol | ALLIED CHEMICAL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11685734-B2 | ATM kinase inhibitors and compositions and methods of use thereof | ATM, CHEK2, CHEK1 | PTGS2 3421/4885PTGS1 3244/4885OPRK1 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.