Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225031 | 1.00 | PTGS2 (0.56) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL4595 | 0.98 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169546 | 0.98 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9790769 | 0.98 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL23056654 | 0.93 | PTGS2 (0.59) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29169544 | 0.93 | PTGS2 (0.59) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL793526 | 0.93 | PTGS2 (0.59) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9145459 | 0.90 | PTGS2 (0.54) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL9144882 | 0.86 | PTGS2 (0.57) | PTGS2PTGS1OPRK1HTTKMT2A | |
| SCHEMBL29016897 | 0.85 | DDB1 (0.61) | PTGS2PTGS1OPRK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352703-B1 | APPLYING POISON AND FEEDING STIMULANT COMPRISING NAPHTHALENE, 2,6-DI-TERT-BUTYL-4-METHYLPHENOL, ERGOSTEROL, DIOCTYL ADIPATE, AND/OR DIOCTYL PHTHALATE; INCREASED CONSUMPTION | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2002-03-05 | — | — | US | disclosed |
| WO-1999029172-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND KILLING TERMITES | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITYAND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 1999-06-17 | — | — | WO | disclosed |
| US-4511569-A | Tricyclic lactams and derivatives useful in increasing cardiac contractility | SCHERING CORPORATION (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0102046-A1 | Tricyclic lactams, method for making them, pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-03-07 | — | — | EP | disclosed |
| US-3937710-A | BENZYL-SUBSTITUTED CYCLOOCTANONES | R. J. REYNOLDS TOBACCO COMPANY (US) | 1976-02-10 | — | — | US | disclosed |