⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL859772 | 0.94 | FAAH (0.40) | — | |
| SCHEMBL15201267 | 0.92 | FAAH (0.42) | — | |
| SCHEMBL11510236 | 0.92 | FAAH (0.42) | — | |
| SCHEMBL7431163 | 0.92 | FAAH (0.42) | — | |
| SCHEMBL10577731 | 0.92 | FAAH (0.42) | — | |
| SCHEMBL543465 | 0.92 | FAAH (0.42) | — | |
| SCHEMBL18649069 | 0.92 | FAAH (0.42) | — | |
| Fluoride SCHEMBL28689077 | 0.92 | FAAH (0.39) | — | |
| Bromide SCHEMBL29849486 | 0.90 | FAAH (0.41) | — | |
| SCHEMBL6012846 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080105-A1 | SUBSTITUTED DIALKYL(OXIDO)-LAMBDA4-SULFANYLIDENE NICOTINAMIDE DERIVATIVES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2016-10-19 | — | — | EP | claimed |
| WO-2015089210-A1 | SUBSTITUTED DIALKYL(OXIDO)-Λ4-SULFANYLIDENE NICOTINAMIDE DERIVATIVES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2015-06-18 | — | — | WO | claimed |
| CN-101747597-A | Conductive master batch and conductive single fiber | TAIWAN TEXTILE RES INST | 2010-06-23 | — | — | CN | claimed |
| WO-2008105607-A1 | HETEROARYL-IMIDAZOLE DERIVATIVES AS CANNABINOID CB1 RECEPTOR ANTAGONISTS | GREEN CROSS CORPORATION (KR) | 2008-09-04 | — | — | WO | claimed |
| US-7163933-B2 | Treating agent for Paget's disease of bone | TEIJIN LIMITED (JP) | 2007-01-16 | — | — | US | claimed |
| US-20030191094-A1 | Treating agent for Paget's disease of bone | TEIJIN LIMITED | 2003-10-09 | — | — | US | claimed |
| EP-1342796-A2 | Compound for the treatment of paget's disease of bone | TEIJIN LIMITED (JP) | 2003-09-10 | — | — | EP | claimed |
| JP-2002524392-A | — | — | 2002-08-06 | — | — | JP | claimed |
| EP-1100802-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M Innovative Properties Company (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006577-A1 | OXAZOLO, THIAZOLO AND SELENAZOLO [4,5-c]-QUINOLIN-4-AMINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-02-10 | — | — | WO | claimed |
| CN-115784815-B | Butyloxapol flame retardant material and preparation method and application thereof | 北京理工大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115784815-B | Butyloxapol flame retardant material and preparation method and application thereof | 北京理工大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-116621119-A | Surface coating modified AlH 3 Processing method and application thereof | 湖北航天化学技术研究所 | 2023-08-22 | — | — | CN | disclosed |
| CN-112595630-B | Device and method for testing leveling property of solid propellant slurry | 上海航天化工应用研究所 | 2023-05-09 | — | — | CN | disclosed |
| EP-4126852-A1 | AZASPIROCYCLES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| EP-1340780-A1 | METAL CATALYST FOR RING-OPENING POLYMERIZATION OF HETEROCYCLIC COMPOUND | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-1240153-A1 | AMINOTHIAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | Bristol-Myers Squibb Company (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001044217-A1 | AMINOTHIAZOLE INHIBITORS OF CYCLIN DEPENDENT KINASES | BRISTOL-MYERS SQUIBB CO. (US) | 2001-06-21 | — | — | WO | disclosed |
| CN-1023227-C | Prepn. of 2,5-dibenzoxazolyl thiophene | WUHAN CHEMICAL INDUSTRY INST (CN) | 1993-12-22 | — | — | CN | disclosed |
| EP-0104157-B1 | RUBBER COMPOSITIONS CONTAINING A VULCANIZATION SYSTEM ALTERATIVE | Monsanto Company (US) | 1986-04-02 | — | — | EP | disclosed |