Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510236 | 1.00 | FAAH (0.42) | FAAHCES1KCNH2TLR7PPARA | |
| SCHEMBL15201267 | 1.00 | FAAH (0.42) | FAAHCES1KCNH2TLR7PPARA | |
| SCHEMBL18649069 | 1.00 | FAAH (0.42) | FAAHCES1KCNH2TLR7PPARA | |
| SCHEMBL10577731 | 1.00 | FAAH (0.42) | FAAHCES1KCNH2TLR7PPARA | |
| SCHEMBL7431163 | 1.00 | FAAH (0.42) | FAAHCES1KCNH2TLR7PPARA | |
| Bromide SCHEMBL29849486 | 0.98 | FAAH (0.41) | FAAHCES1KCNH2TLR7PPARA | |
| SCHEMBL859772 | 0.98 | FAAH (0.40) | FAAHCES1KCNH2TLR7PPARA | |
| Fluoride SCHEMBL28689077 | 0.96 | FAAH (0.39) | FAAHCES1KCNH2TLR7PPARA | |
| SCHEMBL4595010 | 0.92 | — | — | |
| SCHEMBL13662366 | 0.90 | FAAH (0.56) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1791598-A | benzimidazole derivatives as factor Xa inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-06-21 | — | — | CN | claimed |
| CN-1791601-A | azaindole derivatives as factor Xa inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-06-21 | — | — | CN | claimed |
| US-9999619-B2 | Piperidin-4-yl azetidine derivatives as JAK1 inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-20170246157-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | INCYTE CORPORATION | 2017-08-31 | — | — | US | disclosed |
| EP-2414367-B1 | PROSTAGLANDIN E RECEPTOR ANTAGONISTS | ALLERGAN INC (US) | 2014-08-13 | — | — | EP | disclosed |
| EP-2414367-A1 | PROSTAGLANDIN E RECEPTOR ANTAGONISTS | Allergan, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114997-A1 | PROSTAGLANDIN E RECEPTOR ANTAGONISTS | ALLERGAN, INC. (US) | 2010-10-07 | — | — | WO | disclosed |
| CN-100484935-C | benzimidazole derivatives as factor Xa inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | CN | disclosed |
| CN-1791601-A | azaindole derivatives as factor Xa inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-06-21 | — | — | CN | disclosed |
| CN-1791598-A | benzimidazole derivatives as factor Xa inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-06-21 | — | — | CN | disclosed |
| US-7045634-B2 | Prostamide receptor antagonists | ALLERGAN, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20020165399-A1 | Interphenylene 7-oxabicyclic [2.2.1] heptane oxazoles as prostaglandin F2a antagonists | ALLERGAN SALES, INC. | 2002-11-07 | — | — | US | disclosed |
| US-20020165399-A1 | Interphenylene 7-oxabicyclic [2.2.1] heptane oxazoles as prostaglandin F2a antagonists | ALLERGAN SALES, INC. | 2002-11-07 | — | — | US | disclosed |
| US-20020128233-A1 | Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2alpha antagonists | ALLERGAN, INC. | 2002-09-12 | — | — | US | disclosed |
| US-6407250-B1 | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS; OSTEOPOROSIS | ALLERGAN SALES, INC. | 2002-06-18 | — | — | US | disclosed |
| US-6407250-B1 | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS; OSTEOPOROSIS | ALLERGAN SALES, INC. | 2002-06-18 | — | — | US | disclosed |
| WO-2002022621-A2 | INTERPHENYLENE 7-OXABICYCLIC[2.2.1]HEPTANE OXAZOLES AS PROSTAGLANDIN F2a ANTAGONISTS | ALLERGAN INC. (US) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022620-A2 | INTERHETEROARYL 7-OXABICYCLIC [2.2.1]HEPTANE OXAZOLES AS PROSTAGLANDIN F2$G(A) ANTAGONISTS | ALLERGAN, INC. (US) | 2002-03-21 | — | — | WO | disclosed |
| EP-0507790-A1 | PROCESS FOR PREPARING CROSSLINKED POLYMERS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-10-14 | — | — | EP | disclosed |
| WO-1991009897-A2 | PROCESS FOR PREPARING CROSSLINKED POLYMERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165399-A1 | Interphenylene 7-oxabicyclic [2.2.1] heptane oxazoles as prostaglandin F2a antagonists | PTGIR, PTGER1, TBXA2R | FAAH 620/4885CES1 2273/4885KCNH2 3351/4885 |
| US-20020128233-A1 | Interheteroaryl 7-oxabicyclic [2.2.1]heptane oxazoles as prostaglandin F2alpha antagonists | PTGER1, PTGIR, PTGDR | FAAH 687/4885CES1 2617/4885KCNH2 3152/4885 |
| US-20170246157-A1 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | JAK1, JAK2, JAK3 | FAAH 3480/4885CES1 2884/4885KCNH2 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.