SCHEMBL4595078

SCHEMBL4595078

C=C(C)C(=O)OC(Br)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.44
ELANE P08246 1/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 1/20 0.41
KMT2A Q03164 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HCAR2 Q8TDS4 1/20 0.37
CYP2D6 P10635 1/20 0.36
SRC P12931 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HSD17B10 Q99714 1/20 0.35
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1131746 0.83 ESR1 (0.49) HPGDELANEALDH1A1CYP3A4KMT2A
SCHEMBL1437800 0.81 ALDH1A1 (0.47) HPGDELANECES2CES1ALDH1A1
SCHEMBL777870 0.81 ALDH1A1 (0.55) HPGDCES2CES1ALDH1A1CYP3A4
SCHEMBL10907558 0.80 HCAR2 (0.53) HPGDELANEALDH1A1CYP3A4KMT2A
SCHEMBL21768706 0.80 HPGD (0.46) HPGDELANECES2CES1ALDH1A1
SCHEMBL962438 0.80 HPGD (0.50) HPGDELANECES2CES1ALDH1A1
SCHEMBL41864 0.80 HCAR2 (0.53) HPGDELANEALDH1A1CYP3A4KMT2A
SCHEMBL8013057 0.79 HPGD (0.44) HPGDELANEALDH1A1CYP3A4KMT2A
SCHEMBL527905 0.79 HPGD (0.44) HPGDELANECES2CES1ALDH1A1
SCHEMBL8366247 0.79 ALDH1A1 (0.49) HPGDELANEALDH1A1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112778710-A high-PTI (polybutylene terephthalate) and high-toughness PBT (polybutylene terephthalate) composition as well as preparation method and application thereof 金发科技股份有限公司 2021-05-11 CN claimed
CN-107108797-B Bromine-containing polymer and process for producing the same 玛耐科股份有限公司 2020-01-10 CN disclosed
CN-109676978-A Increasing material manufacturing method for transparent glasses piece 依视路国际公司 2019-04-26 CN disclosed
CN-103946249-B Conjugated diolefin polymer and manufacture method thereof 日本瑞翁株式会社 2016-08-24 CN disclosed
CN-105829922-A Polymer Composition And Methods Using Said Polymer Composition To Manufacture Ophthalmic Lens 埃西勒国际通用光学公司 2016-08-03 CN disclosed
CN-105431283-A Additive manufacturing for transparent ophthalmic lens ESSILOR INT CIE GENERALE D OPTIQUE 2016-03-23 CN disclosed
CN-105392618-A Additive manufacturing method for transparent ophthalmic lenses ESSILOR INT CIE GENERALE D'OPTIQUE 2016-03-09 CN disclosed
CN-102029756-B Transparent conductive film FUJIFILM CORP 2015-07-15 CN disclosed
CN-102029756-A Transparent conductive film FUJIFILM CORP 2011-04-27 CN disclosed
CN-100504448-C Activation-energy-ray-curable resin composition for lens sheet and lens sheet DAINIPPON INK & CHEMICALS DAIN (JP) 2009-06-24 CN disclosed
US-6132931-A A FLUORINE-CONTAINING POLYURETHANE COPOLYMER; FORMING A HIGH CONTRAST IMAGE, INHIBITING HALATION, A SAFE LIGHT TOLERANCE AND A WIDE DEVELOPMENT LATITUDE, WITHOUT LOWERING THE SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 2000-10-17 US disclosed
US-6110640-A Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2000-08-29 US disclosed
EP-0949539-A2 Photosensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1999-10-13 EP disclosed
EP-0843218-A1 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1998-05-20 EP disclosed
US-5155190-A Suspension polymerization, excellent heat resistance, weatherproofing and transparency HITACHI CHEMICAL COMPANY (JP) 1992-10-13 US disclosed
US-RE34061-E And one or more unsaturated monomes; transparency, heat and moisture resistance optical elements HITACHI CHEMICAL CO., LTD. (JP) 1992-09-08 US disclosed
EP-0317263-A2 Optical material JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-05-24 EP disclosed
US-4591626-A TRANSPARENT OPTICAL MATERIALS HITACHI CHEMICAL COMPANY, LTD. (JP) 1986-05-27 US disclosed
EP-0141610-A2 Optical elements comprising polymers of (meth)acrylate esters Hitachi Chemical Co., Ltd. (JP) 1985-05-15 EP disclosed
US-4369298-A Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1983-01-18 US disclosed