Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL8503430 | 0.98 | TSHR (0.43) | LMNAMAPTTSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL28622525 | 0.96 | GPR84 (0.41) | LMNAMAPTTSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL28673504 | 0.96 | TDP1 (0.41) | LMNAMAPTTSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL9778978 | 0.96 | TDP1 (0.41) | LMNAMAPTTSHRNFKB1PMP22 | |
| Adipic Acid SCHEMBL537049 | 0.96 | TDP1 (0.41) | LMNAMAPTTSHRNFKB1PMP22 | |
| Glutarate SCHEMBL20504491 | 0.96 | SLC22A6 (0.41) | LMNAMAPTTSHRNFKB1PMP22 | |
| Hexanoate SCHEMBL28739919 | 0.93 | AKR1B1 (0.52) | MAPTTSHRTDP1GPR84FFAR1 | |
| Hexanoate SCHEMBL1171519 | 0.93 | AKR1B1 (0.52) | MAPTTSHRTDP1GPR84FFAR1 | |
| Adipic Acid SCHEMBL2963356 | 0.93 | MAPT (0.36) | LMNAMAPTTSHRNFKB1PMP22 | |
| Succinic Acid SCHEMBL29008437 | 0.92 | TDP1 (0.41) | LMNAMAPTTDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117801226-A | Matrine-containing antibacterial anionic aqueous polyurethane and preparation method thereof | 山西省应用化学研究所(有限公司) | 2024-04-02 | — | — | CN | claimed |
| CN-116284671-B | Heparin-like polyurethane with self-repairing performance and preparation method and application thereof | 苏州心锐医疗科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116284671-A | Heparin-like polyurethane with self-repairing performance and preparation method and application thereof | 苏州心锐医疗科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116042162-A | Preparation of high-heat-resistance high-solid-content single-component aqueous polyurethane automotive interior adhesive | 碧优新材料(广州)有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-111218251-A | Polyurethane adhesive for ETPU track molding and preparation method thereof | 高鼎精细化工(昆山)有限公司 | 2020-06-02 | — | — | CN | claimed |
| CN-103724914-A | Sheet molding compound for producing A-level surface products and preparation method thereof | BEIJING AUTOMOBILE GLASS FIBER REINFORCED PLASTIC CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-102618204-B | Hot-melt adhesive for bonding layer of artificial leather and preparation method as well as application thereof | JIANGYIN NUOKE SCIENCE AND TECHNOLOGY CO LTD | 2013-11-27 | — | — | CN | claimed |
| CN-102618204-A | Hot-melt adhesive for bonding layer of artificial leather and preparation method as well as application thereof | JIANGYIN NUOKE SCIENCE AND TECHNOLOGY CO LTD | 2012-08-01 | — | — | CN | claimed |
| CN-101831153-B | Composition and flake moulding materials prepared by combination | BEIJING FRP AUTO PARTS CORP LTD | 2012-07-25 | — | — | CN | claimed |
| CN-101831153-A | Composition and flake moulding materials prepared by combination | BEIJING FRP AUTO PARTS CORP LTD | 2010-09-15 | — | — | CN | claimed |
| JP-55082155-A | — | — | None | — | — | JP | disclosed |
| US-20260069734-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | ARYLESSENCE INC (US) | 2026-03-12 | — | — | US | disclosed |
| CN-117801226-A | Matrine-containing antibacterial anionic aqueous polyurethane and preparation method thereof | 山西省应用化学研究所(有限公司) | 2024-04-02 | — | — | CN | disclosed |
| CN-116284671-B | Heparin-like polyurethane with self-repairing performance and preparation method and application thereof | 苏州心锐医疗科技有限公司 | 2023-08-08 | — | — | CN | disclosed |
| CN-108084861-B | Self-repairing oil stain-proof coating and preparation method thereof, protective film containing coating and preparation method thereof | 常州山由帝杉防护材料制造有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-4132840-A | Process for coloring polyurethane foams | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |
| US-4038240-A | PROCESS FOR DYEING POLYURETHANE RESINS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-26 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3994835-A | Process for the production of colored polyurethane foams | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |
| US-3993619-A | AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260069734-A1 | FRESHENING COMPOSITIONS COMPRISING CONTROLLED RELEASE MODULATORS | FFAR1, FFAR2, FFAR3 | LMNA 399/4885MAPT 4109/4885TSHR 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.