SCHEMBL4595526

SCHEMBL4595526

C=C(F)/C(F)=C/CCCC

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 1/20 0.40
EP300 Q09472 1/20 0.34
GRIK1 P39086 1/20 0.32
MEN1 O00255 1/20 0.31
CYP3A4 P08684 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4595528 1.00 TSHR (0.40) TSHRALDH1A1EP300GRIK1MEN1
SCHEMBL7178111 0.85
SCHEMBL7178109 0.85
SCHEMBL3908467 0.79
SCHEMBL28634767 0.75
SCHEMBL9712144 0.74 EP300 (0.52) TSHREP300GRIK1KMT2A
SCHEMBL15546702 0.74 EP300 (0.52) TSHREP300GRIK1KMT2A
SCHEMBL8168766 0.74 ALDH1A1 (0.35) TSHRALDH1A1MEN1CYP3A4KMT2A
SCHEMBL22111945 0.74
SCHEMBL4595323 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451121-B1 OPTICAL FIBER WITH EPOXIDIZED POLYOLEFIN BASED COATING PRYSMIAN CAVI SISTEMI ENERGIA (IT) 2008-01-09 EP disclosed
US-7120343-B2 Optical fiber with epoxidized polyolefin based coating PERELLI & C. S.P.A. (IT) 2006-10-10 US disclosed
US-20060056790-A1 Optical fiber with epoxidized polyolefin based coating PIRELLI & C S.P.A. 2006-03-16 US disclosed
US-6996318-B2 Optical fiber with epoxidized polyolefin based coating PIRELLI & C. S.P.A. (IT) 2006-02-07 US disclosed
US-20050089297-A1 Optical fiber with epoxidized polyolefin based coating PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) 2005-04-28 US disclosed
WO-2003057645-A1 OPTICAL FIBER WITH EPOXIDIZED POLYOLEFIN BASED COATING PIRELLI & C. S.P.A. (IT) 2003-07-17 WO disclosed
WO-2002096180-A1 A RADIATION CURABLE PRIMARY COATING COMPOSITION FOR AN OPTICAL FIBER ALVIN C. LEVY & ASSOCIATES, INC. (US) 2002-12-05 WO disclosed
US-6042943-A PROTECTIVE COATING FOR RELIEVING STRESS WHEN FIBER IS BENT, CABLED, AND SPOOLED ALVIN C. LEVY & ASSOCIATES, INC. (US) 2000-03-28 US disclosed
US-5985952-A CURABLE COATINGS FOR OPTICAL FIBERS WITH EPOXIDE GROUPS AND ACRYLATE MONOMERS ALVIN C. LEVY & ASSOCIATES, INC. (US) 1999-11-16 US disclosed
US-4879349-A CONJUGATED OLEFIN POLYMER SHELL OIL COMPANY (US) 1989-11-07 US disclosed
EP-0315280-A2 Selective hydrogenation process SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-05-10 EP disclosed