SCHEMBL4595556

SCHEMBL4595556

Cc1ccc2nc3ccc(C)cc3c(-c3ccc(Cl)c(Cl)c3)c2c1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
IKBKB O14920 1/20 0.43
MAPK1 P28482 1/20 0.43
AHR P35869 2/20 0.42
ALKBH3 Q96Q83 1/20 0.42
DHODH Q02127 2/20 0.42
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
MAP3K14 Q99558 1/20 0.40
HSP90AB1 P08238 1/20 0.40
KMO O15229 1/20 0.40
ELANE P08246 1/20 0.39
EIF4E P06730 1/20 0.39
NQO2 P16083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29660708 1.00 LMNA (0.53) LMNAMAPTKDM4EALDH1A1IKBKB
SCHEMBL6269076 0.84 MAP3K14 (0.46) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL29660592 0.84 LMNA (0.50) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL5361837 0.84 LMNA (0.50) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL29660676 0.82 LMNA (0.48) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL4596628 0.82 LMNA (0.48) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL4596211 0.77 KDM4E (0.57) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL29660570 0.77 KDM4E (0.57) LMNAMAPTKDM4EALDH1A1DHODH
SCHEMBL21799184 0.76 ALDH1A1 (0.64) LMNAMAPTKDM4EALDH1A1MAPK1
SCHEMBL913577 0.75 ELANE (0.56) LMNAMAPTKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5583133-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-12-10 US claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
CN-110114376-B Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2022-06-14 CN disclosed
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
CN-108419438-B Coloring composition 株式会社艾迪科 2021-10-01 CN disclosed
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 CN disclosed
CN-111566173-A Coating composition, method for curing the composition, barrier film, and method for producing cured product 株式会社艾迪科 2020-08-21 CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 WO disclosed
EP-1877864-B1 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF MERCK PATENT GMBH (DE) 2018-09-19 EP disclosed
EP-1877864-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ Electronic Materials USA Corp. (US) 2008-01-16 EP disclosed
US-7247419-B2 Nanocomposite photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2007-07-24 US disclosed
US-20070141510-A1 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF CHEN CHUNWEI 2007-06-21 US disclosed
WO-2006109121-A2 NANOCOMPOSITE PHOTOSENSITIVE COMPOSITION AND USE THEREOF AZ ELECTRONIC MATERIALS USA CORP. (DE) 2006-10-19 WO disclosed
US-20060228645-A1 Nanocomposite photosensitive composition and use thereof MERCK PATENT GMBH (DE) 2006-10-12 US disclosed
US-7078157-B2 Photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. (US) 2006-07-18 US disclosed
US-20040175653-A1 Photosensitive composition and use thereof AZ ELECTRONIC MATERIALS USA CORP. 2004-09-09 US disclosed
EP-0374704-B1 Photopolymerisable blend and photopolymerisable recording material containing it MORTON INT INC (US) 1996-03-27 EP disclosed
US-5217845-A 9-Arylacridine as photoinitiator HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-08 US disclosed
EP-0374704-A2 Photopolymerisable blend and photopolymerisable recording material containing it MORTON INTERNATIONAL, INC. (US) 1990-06-27 EP disclosed