SCHEMBL4595650

SCHEMBL4595650

CC(C)C1CCC(C)(OCC(O)CO)CC1OC1CC(C)(OCC(O)CO)CCC1C(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.30
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119537 0.84 TRPA1 (0.33)
SCHEMBL4594905 0.84 TRPA1 (0.33)
SCHEMBL2349957 0.80 SLC1A2 (0.31)
SCHEMBL4594908 0.77
SCHEMBL375500 0.76 USP2 (0.32)
SCHEMBL121847 0.76 USP2 (0.32)
SCHEMBL2363468 0.76 USP2 (0.32)
SCHEMBL18105981 0.74 LMNA (0.38) LMNAKDM4EAPOBEC3AAPOBEC3GGAA
SCHEMBL3131739 0.69
SCHEMBL21300577 0.67 TRPA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1541039-B1 Flavour composition comprising cubebol and a further refreshing agent FIRMENICH & CIE (CH) 2008-01-02 EP claimed
EP-1541039-A1 Flavour composition comprising cubebol and a further refreshing agent FIRMENICH SA (CH) 2005-06-15 EP claimed
EP-1541039-B1 Flavour composition comprising cubebol and a further refreshing agent FIRMENICH & CIE (CH) 2008-01-02 EP disclosed
EP-1541039-A1 Flavour composition comprising cubebol and a further refreshing agent FIRMENICH SA (CH) 2005-06-15 EP disclosed
US-6214788-B1 PERFUMES AND FLAVORS FIRMENICH SA (CH) 2001-04-10 US disclosed
EP-1040765-A1 Use of cubebol as a flavoring ingredient FIRMENICH SA (CH) 2000-10-04 EP disclosed