SCHEMBL4595683

SCHEMBL4595683

CC1C=Cc2ccccc2N1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
P2RX4 Q99571 6/20 0.38
P2RX1 P51575 2/20 0.38
P2RX3 P56373 2/20 0.38
P2RX7 Q99572 2/20 0.38
GPR3 P46089 1/20 0.37
LMNA P02545 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
TSHR P16473 2/20 0.34
MAPK1 P28482 2/20 0.34
SCN4A P35499 1/20 0.34
SCN5A Q14524 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20651294 1.00 MEN1 (0.51) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL30100361 1.00 MEN1 (0.51) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL31535960 0.91 MEN1 (0.45) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL28904922 0.78 GPR3 (0.39) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL23346968 0.78 MEN1 (0.39) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL3253414 0.78 MEN1 (0.42) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL28877058 0.77 MEN1 (0.50) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL20870362 0.75 SMN1; SMN2 (0.39) MEN1KMT2ALMNASMN1; SMN2ALDH1A1
SCHEMBL22202241 0.75 SMN1; SMN2 (0.43) MEN1KMT2AP2RX4P2RX1P2RX3
SCHEMBL4595897 0.75 KMT2A (0.47) MEN1KMT2AP2RX4P2RX1P2RX3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777018-A Fluorescent probe for detecting viscosity and pH through double channels, and preparation method and application thereof 新乡医学院 2024-03-29 CN claimed
CN-117263858-A Double-quinoline NADH fluorescent probe and preparation method thereof 南通大学 2023-12-22 CN claimed
CN-115632148-B Hybrid power generation system and method 北京海望氢能科技有限公司 2023-03-21 CN claimed
CN-115632148-A Hybrid power generation system and method 北京海望氢能科技有限公司 2023-01-20 CN claimed
CN-113831653-B Ethylene propylene diene monomer rubber material for wire drawing machine manipulator clamping jaw and preparation method thereof 中国建筑材料科学研究总院有限公司 2023-01-10 CN claimed
CN-113831653-A Ethylene propylene diene monomer rubber material for wire drawing machine manipulator clamping jaw and preparation method thereof 中国建筑材料科学研究总院有限公司 2021-12-24 CN claimed
CN-109574922-A A kind of mitochondrial membrane potential fluorescence probe and its synthetic method and application 济南大学 2019-04-05 CN claimed
CN-108373447-A A kind of fluorescence probe that distinguishing dead/living cells and its synthetic method and application 济南大学 2018-08-07 CN claimed
CN-105018208-A High temperature-resistant water spraying-resistant radiation-resistant wear-resistant lubricating grease composition UNIV GUANGXI 2015-11-04 CN claimed
CN-104962374-A Lubricating grease composition for long-service life and wide-temperature antirust vehicle door checks UNIV GUANGXI 2015-10-07 CN claimed
EP-1537851-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-06-08 EP claimed
EP-1537852-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-06-08 EP claimed
EP-1194117-B1 AGENT FOR DYEING KERATIN CONTAINING FIBRES HENKEL KGAA (DE) 2005-06-01 EP claimed
EP-1535601-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-06-01 EP claimed
EP-1535600-A1 Use of derivatives of ninhydrin carrying an unsaturated system in colouring L'OREAL (FR) 2005-06-01 EP claimed
EP-1530963-A1 Use of ninhydrin derivatives in colouring L'OREAL (FR) 2005-05-18 EP claimed
EP-1194116-B1 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KGAA (DE) 2005-05-04 EP claimed
EP-1502580-A1 Use in dyeing of aromatic polycyclic vicinal triones with condensed cycles L'OREAL (FR) 2005-02-02 EP claimed
EP-1500387-A1 Use of ninhydrin derivatives for dyeing L'OREAL (FR) 2005-01-26 EP claimed
EP-1139990-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2004-05-06 EP claimed