Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595958 | 1.00 | TSHR (0.39) | TSHRMMEALDH1A1PKMCYP1A2 | |
| SCHEMBL4597621 | 1.00 | TSHR (0.39) | TSHRMMEALDH1A1PKMCYP1A2 | |
| SCHEMBL4597189 | 0.75 | SMN1; SMN2 (0.48) | TSHRMMEALDH1A1PKMMEN1 | |
| SCHEMBL4597186 | 0.75 | SMN1; SMN2 (0.48) | TSHRMMEALDH1A1PKMMEN1 | |
| SCHEMBL4597482 | 0.75 | SMN1; SMN2 (0.48) | TSHRMMEALDH1A1PKMMEN1 | |
| SCHEMBL4595755 | 0.74 | KMT2A (0.41) | TSHRMMECYP1A2CYP2C19PPM1B | |
| SCHEMBL4595752 | 0.74 | KMT2A (0.41) | TSHRMMECYP1A2CYP2C19PPM1B | |
| SCHEMBL4596828 | 0.74 | KMT2A (0.41) | TSHRMMECYP1A2CYP2C19PPM1B | |
| SCHEMBL4597073 | 0.72 | ALDH1A1 (0.68) | TSHRMMEALDH1A1PKMCYP2C19 | |
| SCHEMBL4596961 | 0.72 | ALDH1A1 (0.68) | TSHRMMEALDH1A1PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506177-B1 | PROCESS FOR THE PREPARATION OF THE ENANTIOMERIC FORMS OF 2-SUBSTITUTED 2-(2,5-DIOXOIMIDAZOLIDIN-1-YL)-ACETIC ACID DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-6908752-B2 | Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1yl) -acetic acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-21 | — | — | US | disclosed |
| US-20030054507-A1 | Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1-yl) -acetic acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-03-20 | — | — | US | disclosed |