Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596965 | 1.00 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL4597073 | 1.00 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL1134045 | 0.87 | ALDH1A1 (0.62) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL1563867 | 0.81 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL2304471 | 0.81 | ALDH1A1 (1.00) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL6386661 | 0.80 | ALDH1A1 (0.90) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL7334247 | 0.78 | ALDH1A1 (0.77) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL10536673 | 0.76 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL9326774 | 0.76 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT | |
| SCHEMBL8873673 | 0.76 | ALDH1A1 (0.68) | ALDH1A1PKMGAAKMT2AAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506177-B1 | PROCESS FOR THE PREPARATION OF THE ENANTIOMERIC FORMS OF 2-SUBSTITUTED 2-(2,5-DIOXOIMIDAZOLIDIN-1-YL)-ACETIC ACID DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-6908752-B2 | Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1yl) -acetic acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-21 | — | — | US | disclosed |
| US-20030054507-A1 | Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1-yl) -acetic acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-03-20 | — | — | US | disclosed |