Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595419 | 0.91 | CA12 (0.40) | EPHX2 | |
| SCHEMBL4596150 | 0.88 | AAK1 (0.30) | — | |
| SCHEMBL5548233 | 0.88 | CPN1 (0.37) | — | |
| SCHEMBL5548245 | 0.76 | SIGMAR1 (0.50) | — | |
| SCHEMBL20974179 | 0.74 | — | — | |
| SCHEMBL1439228 | 0.74 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL14910149 | 0.74 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL14910147 | 0.74 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL16164720 | 0.74 | EPHX2 (0.40) | EPHX2 | |
| SCHEMBL15399305 | 0.74 | EPHX2 (0.40) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874768-A2 | INHIBITORS OF AKT ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006113837-A2 | INHIBITORS OF AKT ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2006-10-26 | — | — | WO | disclosed |