Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595970 | 0.80 | CTSL (0.41) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL19879722 | 0.74 | CTSL (0.39) | MAPTCTSL | |
| SCHEMBL5576653 | 0.72 | BCHE (0.45) | EPHX2NPC1RAB9ACACNA1BCTSL | |
| SCHEMBL29949477 | 0.70 | CTSL (0.42) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL26257358 | 0.70 | CTSL (0.42) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL25399092 | 0.70 | CTSL (0.42) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL19731493 | 0.69 | CTSL (0.42) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL24944766 | 0.69 | CTSL (0.42) | NPC1RAB9AMAPTHPGDSMN1; SMN2 | |
| SCHEMBL25402601 | 0.69 | CTSL (0.48) | CTSL | |
| SCHEMBL29949243 | 0.69 | CTSL (0.41) | MAPTHPGDSMN1; SMN2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |