Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRND | Q07001 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25399092 | 0.87 | CTSL (0.42) | CTSLMAPTKDM4EHPGDSLC6A2 | |
| SCHEMBL26257358 | 0.87 | CTSL (0.42) | CTSLMAPTKDM4EHPGDSLC6A2 | |
| SCHEMBL29949477 | 0.87 | CTSL (0.42) | CTSLMAPTKDM4EHPGDSLC6A2 | |
| SCHEMBL25395803 | 0.86 | MAPT (0.39) | CTSLMAPTKDM4ESLC6A2CYP2C19 | |
| SCHEMBL26965566 | 0.85 | PKM (0.40) | MAPTHPGDSLC6A2CYP2C19CHRNA1 | |
| SCHEMBL25402190 | 0.85 | RXFP1 (0.46) | MAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20117837 | 0.81 | MAPT (0.50) | MAPTHPGDCYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL24944766 | 0.78 | CTSL (0.42) | CTSLMAPTKDM4EHPGDCYP2C19 | |
| SCHEMBL19731493 | 0.78 | CTSL (0.42) | CTSLMAPTKDM4EHPGDCYP2C19 | |
| SCHEMBL25402601 | 0.77 | CTSL (0.48) | CTSLKDM4EAKT1IDO1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11945811-B2 | Potassium channel inhibitors | ACESION PHARMA APS (DK) | 2024-04-02 | — | — | US | disclosed |
| EP-4313973-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | Acesion Pharma ApS (DK) | 2024-02-07 | — | — | EP | disclosed |
| US-20230406845-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACESION PHARMA APS (DK) | 2023-12-21 | — | — | US | disclosed |
| WO-2022200162-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | ACECION PHARMA APS (DK) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11945811-B2 | Potassium channel inhibitors | KCNJ2, KCNN2, KCNN1 | CTSL 3805/4885MAPT 1789/4885KDM4E 1829/4885 |
| US-20230406845-A1 | NOVEL POTASSIUM CHANNEL INHIBITORS | KCNN2, KCNJ2, KCNN1 | CTSL 3759/4885MAPT 2025/4885KDM4E 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.