Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010099 | 0.77 | CA1 (0.33) | — | |
| SCHEMBL9276620 | 0.76 | MAPT (0.32) | MEN1KMT2A | |
| SCHEMBL18434998 | 0.76 | MAPT (0.32) | MEN1KMT2A | |
| SCHEMBL21628145 | 0.76 | MAPT (0.32) | MEN1KMT2A | |
| SCHEMBL30258679 | 0.75 | — | — | |
| SCHEMBL28249672 | 0.75 | TSHR (0.36) | — | |
| SCHEMBL24788125 | 0.73 | THRB (0.44) | THRBMEN1KMT2A | |
| SCHEMBL10533313 | 0.73 | THRB (0.44) | THRBMEN1KMT2A | |
| SCHEMBL22779289 | 0.71 | CTDSP1 (0.32) | — | |
| SCHEMBL11283293 | 0.71 | MAPT (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110308790-A1 | IN SITU METHANOGENESIS MODELING AND RISK ANALYSIS | CONOCOPHILLIPS COMPANY (US) | 2011-12-22 | — | — | US | claimed |
| WO-2011159919-A2 | IN SITU METHANOGENESIS MODELING AND RISK ANALYSIS | CONOCOPHILLIPS COMPANY (US) | 2011-12-22 | — | — | WO | claimed |
| US-10358660-B2 | Compositions and methods for identifying and modifying carbonaceous compositions | TAXON BIOSCIENCES, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-10221432-B2 | In situ methanogenesis modeling and risk analysis | CONOCOPHILLIPS COMPANY (US) | 2019-03-05 | — | — | US | disclosed |
| EP-2582846-B1 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS | TAXON BIOSCIENCES INC (US) | 2018-11-28 | — | — | EP | disclosed |
| US-20180223316-A1 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS | TAXON BIOSCIENCES INC. (US) | 2018-08-09 | — | — | US | disclosed |
| US-20180163234-A1 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS | TAXON BIOSCIENCES, INC. (US) | 2018-06-14 | — | — | US | disclosed |
| US-20160108435-A1 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS | TAXON BIOSCIENCES INC (US) | 2016-04-21 | — | — | US | disclosed |
| US-9206680-B2 | Compositions and methods for identifying and modifying carbonaceous compositions | TAXON BIOSCIENCES INC (US) | 2015-12-08 | — | — | US | disclosed |
| US-20130116126-A1 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS | TAXON BIOSCIENCES, INC. (US) | 2013-05-09 | — | — | US | disclosed |
| EP-2582846-A2 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND MODIFYING CARBONACEOUS COMPOSITIONS | Taxon Biosciences, Inc. (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-1885704-B1 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF | ABBOTT LAB (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20110144057-A1 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | US | disclosed |
| US-7902236-B2 | Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof | ABBOTT LABORATORIES (US) | 2011-03-08 | — | — | US | disclosed |
| US-20100010055-A1 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF | ABBOTT LABORATORIES (US) | 2010-01-14 | — | — | US | disclosed |
| US-7504520-B2 | Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof | ABBOTT LABORATORIES (US) | 2009-03-17 | — | — | US | disclosed |
| CN-101248052-A | Vanilloid receptor subtype 1(VR1) antagonists and uses thereof | ABBOTT LAB (US) | 2008-08-20 | — | — | CN | disclosed |
| EP-1885704-A2 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF | Abbott Laboratories (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20060281799-A1 | Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof | ABBVIE INC. | 2006-12-14 | — | — | US | disclosed |
| WO-2006122250-A2 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USES THEREOF | ABBOTT LABORATORIES (US) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281799-A1 | Antagonists of the vanilloid receptor subtype 1 (VR1) and use thereof | TRPV1, TMEM109, CACNA1E | THRB 1193/4885MEN1 3283/4885KMT2A 3658/4885 |
| US-20110144057-A1 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF | TRPV1, TMEM109, CACNA1E | THRB 1193/4885MEN1 3283/4885KMT2A 3658/4885 |
| US-20100010055-A1 | ANTAGONISTS OF THE VANILLOID RECEPTOR SUBTYPE 1 (VR1) AND USE THEREOF | TRPV1, TMEM109, CACNA1E | THRB 1193/4885MEN1 3283/4885KMT2A 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.