Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21635498 | 0.86 | ALDH1A1 (0.50) | LMNACYP3A4TSHRRECQLADRA2A | |
| SCHEMBL12229096 | 0.80 | MAPT (0.41) | LMNACYP3A4TSHRRECQLADRA2A | |
| SCHEMBL4811576 | 0.77 | SELL (0.42) | LMNACYP3A4TSHRRECQLADRA2A | |
| SCHEMBL10934796 | 0.77 | CA1 (0.63) | LMNACA12CA1CA2CA7 | |
| SCHEMBL55730 | 0.77 | CYP3A4 (0.52) | LMNACYP3A4TSHRRECQLACHE | |
| SCHEMBL9187399 | 0.75 | GPR84 (0.51) | CYP3A4ADRA2APTGS2 | |
| Hydrochloric Acid SCHEMBL3066468 | 0.75 | CYP3A4 (0.50) | LMNACYP3A4TSHRRECQLACHE | |
| SCHEMBL27746749 | 0.75 | CYP3A4 (0.50) | LMNACYP3A4TSHRRECQLACHE | |
| SCHEMBL440145 | 0.74 | MAPT (0.57) | LMNACYP3A4TSHRRECQLADRA2A | |
| Bromide SCHEMBL4725114 | 0.72 | MAPT (0.55) | LMNACYP3A4TSHRRECQLADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115584093-A | Fluororubber for valves and preparation method thereof | 安徽道格思新材料有限公司 | 2023-01-10 | — | — | CN | claimed |
| CN-109851958-B | High-hardness fluororubber and preparation method thereof | 成都菁尚科技有限公司 | 2020-12-29 | — | — | CN | claimed |
| CN-109467855-A | A kind of fluorubber of high temperature and pressure contracting ratio | 江苏奥纳森弹性体技术研究院有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109401144-A | A kind of fluoro-rubber composite of high temperature and pressure contracting ratio and its application | 江苏奥纳森弹性体技术研究院有限公司 | 2019-03-01 | — | — | CN | claimed |
| CN-109354809-A | A kind of fluoro-rubber composite of high Shao Er hardness | 江苏奥纳森弹性体技术研究院有限公司 | 2019-02-19 | — | — | CN | claimed |
| CN-115584093-A | Fluororubber for valves and preparation method thereof | 安徽道格思新材料有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-109354809-B | high-Shore-hardness fluororubber composition | 江苏奥纳森弹性体技术研究院有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-109851958-B | High-hardness fluororubber and preparation method thereof | 成都菁尚科技有限公司 | 2020-12-29 | — | — | CN | disclosed |
| CN-109467855-A | A kind of fluorubber of high temperature and pressure contracting ratio | 江苏奥纳森弹性体技术研究院有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109401144-A | A kind of fluoro-rubber composite of high temperature and pressure contracting ratio and its application | 江苏奥纳森弹性体技术研究院有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-109354809-A | A kind of fluoro-rubber composite of high Shao Er hardness | 江苏奥纳森弹性体技术研究院有限公司 | 2019-02-19 | — | — | CN | disclosed |
| US-20090163493-A9 | cell proliferation, such as cancer, inflammation, and angiogenesis; fungal infections; antimalaria; Heat hock protein 90 (HSP-90) inhibitor | SERENEX, INC. | 2009-06-25 | — | — | US | disclosed |
| US-20080096887-A1 | cell proliferation, such as cancer, inflammation, and angiogenesis; fungal infections; antimalaria; Heat hock protein 90 (HSP-90) inhibitor | SERENEX, INC. | 2008-04-24 | — | — | US | disclosed |
| EP-1286647-B1 | OXIDATION DYEING METHOD FOR KERATINOUS FIBERS | HENKEL KGAA (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-0841329-A1 | Method of synthesizing tert-amido-substituted 2-(2'-hydroxyphenyl) benzotriazole compounds in a onestep process | EASTMAN KODAK COMPANY (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5739348-A | NOBLE METAL CATALYZED HYDROGENATION OR NONCATALYTIC REDUCTIVE RING CLOSURE AND DEACYLATION OF SPECIFIED AZO DYE | EASTMAN KODAK COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163493-A9 | cell proliferation, such as cancer, inflammation, and angiogenesis; fungal infections; antimalaria; Heat hock protein 90 (HSP-90) inhibitor | HSP90AA1, HSP90AB1, HSPA4 | LMNA 4650/4885CYP3A4 1143/4885TSHR 3710/4885 |
| US-20080096887-A1 | cell proliferation, such as cancer, inflammation, and angiogenesis; fungal infections; antimalaria; Heat hock protein 90 (HSP-90) inhibitor | HSP90AA1, HSP90AB1, HSPA4 | LMNA 4650/4885CYP3A4 1143/4885TSHR 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.