Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46027 | 0.91 | — | — | |
| SCHEMBL12337178 | 0.89 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13823666 | 0.88 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL18473622 | 0.87 | HCRTR1 (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13962904 | 0.86 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14202054 | 0.86 | KDM1A (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13379143 | 0.83 | OPRM1 (0.33) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14292473 | 0.82 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL19937935 | 0.81 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13825005 | 0.80 | OPRM1 (0.36) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005795-A1 | PROCESS FOR THE SYNTHESIS OF SUBSTITUTED MORPHINANS | ALKERMES, INC. (US) | 2012-01-12 | — | — | WO | disclosed |