Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831142 | 1.00 | OPRM1 (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12091332 | 0.89 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13248810 | 0.89 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12830849 | 0.87 | OPRM1 (0.38) | OPRM1OPRD1OPRK1 | |
| SCHEMBL16541860 | 0.86 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL45963 | 0.80 | OPRM1 (0.35) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10222575 | 0.79 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13962904 | 0.77 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL14202054 | 0.77 | KDM1A (0.36) | OPRM1OPRD1OPRK1 | |
| SCHEMBL12830845 | 0.77 | MAOA (0.33) | OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149633-A1 | PROCESSES AND INTERMEDIATES IN THE PREPARATION OF MORPHINE ANALOGS VIA N-DEMETHYLATION OF N-OXIDES USING CYCLODEHYDRATION REAGENTS | BROCK UNIVERSITY (CA) | 2012-11-08 | — | — | WO | disclosed |
| WO-2009012005-A1 | PREPARATION OF N-ALKYLATED OPIATES BY REDUCTIVE AMINATION | MALLINCKRODT INC. (US) | 2009-01-22 | — | — | WO | disclosed |