SCHEMBL4596673

SCHEMBL4596673

COC(=O)C(Br)c1ccccc1Cl.O=C(O)C(Br)c1ccccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
CXCL8 P10145 1/20 0.41
CASP1 P29466 1/20 0.40
OPRM1 P35372 2/20 0.40
ABCB11 O95342 2/20 0.40
THRB P10828 1/20 0.40
NR1I2 O75469 1/20 0.40
CHRM2 P08172 1/20 0.40
ADRA2A P08913 1/20 0.40
CYP2B6 P20813 1/20 0.40
DRD1 P21728 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40
CYP2C19 P33261 1/20 0.40
OPRK1 P41145 1/20 0.40
HTR2B P41595 1/20 0.40
KCNH2 Q12809 1/20 0.40
P2RY12 Q9H244 1/20 0.40
MEN1 O00255 1/20 0.38
OPRL1 P41146 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14009484 0.94 CASP1 (0.44) KMT2ACASP1OPRM1ABCB11THRB
SCHEMBL661387 0.94 CASP1 (0.44) KMT2ACASP1OPRM1ABCB11THRB
SCHEMBL1417549 0.94 CASP1 (0.44) KMT2ACASP1OPRM1ABCB11THRB
SCHEMBL11383904 0.89 KMT2A (0.48) KMT2AMEN1ALDH1A1
SCHEMBL5112227 0.87 MEN1 (0.46) KMT2ACXCL8CASP1OPRM1MEN1
SCHEMBL8128086 0.87 MEN1 (0.46) KMT2ACXCL8CASP1OPRM1MEN1
SCHEMBL365284 0.87 MEN1 (0.46) KMT2ACXCL8CASP1OPRM1MEN1
SCHEMBL9535176 0.83 CXCL8 (0.46) CXCL8ABCB11ALDH1A1
SCHEMBL11276948 0.81 KMT2A (0.50) KMT2AMEN1ALDH1A1
SCHEMBL5327049 0.78 CASP1 (0.56) KMT2ACASP1CYP2C19MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008068569-A2 PROCESSES FOR THE PREPARATION OF CLOPIDOGREL HYDROCHLORIDE WOCKHARDT RESEARCH CENTRE (IN) 2008-06-12 WO disclosed