SCHEMBL4596678

SCHEMBL4596678

CCCC(c1ccc(O)cc1O)c1ccc(O)cc1O

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYR P14679 5/20 0.50
TP53 P04637 2/20 0.45
ALOX15 P16050 2/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX5 P09917 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CRYAA P02489 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492463 0.88 TYR (0.60) TYRMEN1ALOX5MAPTHTT
SCHEMBL21830416 0.88 TYR (0.60) TYRMEN1ALOX5MAPTHTT
SCHEMBL31545402 0.87 TYR (0.50) TYRTP53ALOX15MEN1CYP3A4
SCHEMBL31544881 0.85 TYR (0.53) TYRTP53ALOX15MEN1CYP3A4
SCHEMBL29492385 0.85 TYR (0.45) TYRTP53ALOX15CYP2D6CYP2C9
SCHEMBL21830417 0.85 TYR (0.45) TYRTP53ALOX15CYP2D6CYP2C9
SCHEMBL31545895 0.84 TYR (0.46) TYRTP53ALOX15MEN1CYP3A4
SCHEMBL4596473 0.84 ALOX15 (0.49) TYRTP53ALOX15CYP2D6CYP2C9
SCHEMBL5439730 0.83 TYR (0.53) TYR
SCHEMBL10620174 0.82 ALOX15 (0.51) TYRTP53ALOX15CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090554-A1 A METHOD OF TREATING DEPRESSION BY IMMUNE MODULATION MYND LIFE SCIENCES INC (CA) 2025-03-20 US disclosed
EP-1437231-B1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API CORP (JP) 2008-01-09 EP disclosed
US-20040241598-A1 Developer for thermal recording material and thermal recording materials NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2004-12-02 US disclosed
EP-1437231-A1 DEVELOPER FOR THERMAL RECORDING MATERIAL AND THERMAL RECORDING MATERIALS API Corporation (JP) 2004-07-14 EP disclosed