Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.75 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.69 |
| ▸ | GSK3B | P49841 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | F3 | P13726 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459670 | 1.00 | HDAC3 (0.75) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL14244673 | 0.86 | HDAC8 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL11707965 | 0.86 | HDAC3 (0.80) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL11707977 | 0.86 | HDAC3 (0.80) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12426306 | 0.86 | HDAC8 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL13253697 | 0.84 | HDAC3 (0.77) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL3292542 | 0.81 | HDAC8 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL3292536 | 0.81 | HDAC8 (1.00) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL17693073 | 0.81 | MAPT (0.88) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL5430052 | 0.81 | HDAC3 (0.67) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8291154-A | — | — | None | — | — | JP | disclosed |
| JP-55024113-A | — | — | None | — | — | JP | disclosed |
| US-8853276-B2 | Guanidine derivatives in cinnamic series | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2014-10-07 | — | — | US | disclosed |
| EP-2614046-B1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) | 2014-08-20 | — | — | EP | disclosed |
| EP-2614046-A1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | Produits Chimiques Auxiliaires et de Synthese (FR) | 2013-07-17 | — | — | EP | disclosed |
| US-20130165507-A1 | NEW GUANIDINE DERIVATIVES IN CINNAMIC SERIES | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2013-06-27 | — | — | US | disclosed |
| WO-2012032257-A1 | NOVEL GUANIDINE DERIVATIVES IN THE CINNAMIC SERIES | PRODUITS CHIMIQUES AUXILIAIRES ET DE SYNTHESE (FR) | 2012-03-15 | — | — | WO | disclosed |
| JP-H08291154-A | PRODUCTION OF 2-TRICHLOROMETHYL-5-SUBSTITUTED-1,3,4-OXADIAZOLE DERIVATIVE | FUJI PHOTO FILM CO LTD | 1996-11-05 | — | — | JP | disclosed |
| US-4232106-A | Photosensitive compositions containing 2-halomethyl-5-vinyl-1,3,4-oxadiazoles as free radical progenitors | FUJI PHOTO FILM CO., LTD. (JP) | 1980-11-04 | — | — | US | disclosed |
| US-4212970-A | PHOTOINITIATORS | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-15 | — | — | US | disclosed |
| JP-S5524113-A | NOVEL 2-HALOMETHYL-5-VINYL-1,3,4-OXADIAZOLE COMPOUND | FUJI PHOTO FILM CO LTD | 1980-02-21 | — | — | JP | disclosed |
| JP-S05524113-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165507-A1 | NEW GUANIDINE DERIVATIVES IN CINNAMIC SERIES | GMPS, UNG, AGER | HDAC3 4240/4885HDAC1 3767/4885HDAC2 3350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.