Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4595682 | 1.00 | ALDH1A1 (0.56) | ALDH1A1PKMKMT2AGAAAADAT | |
| SCHEMBL4596955 | 0.99 | ALDH1A1 (0.57) | ALDH1A1PKMKMT2AGAAAADAT | |
| SCHEMBL4597348 | 0.99 | ALDH1A1 (0.57) | ALDH1A1PKMKMT2AGAAAADAT | |
| SCHEMBL4596824 | 0.82 | ALDH1A1 (0.56) | ALDH1A1PKMKMT2AGAAAADAT | |
| SCHEMBL4596553 | 0.82 | ALDH1A1 (0.56) | ALDH1A1PKMKMT2AGAAAADAT | |
| SCHEMBL4596548 | 0.82 | ALDH1A1 (0.56) | ALDH1A1PKMKMT2AGAAAADAT | |
| SCHEMBL6808172 | 0.80 | ITGB1 (0.47) | POLB | |
| SCHEMBL6806872 | 0.80 | ITGB1 (0.54) | — | |
| SCHEMBL4595768 | 0.78 | L3MBTL1 (0.44) | KMT2ASMN1; SMN2L3MBTL1POLB | |
| SCHEMBL4595759 | 0.78 | L3MBTL1 (0.44) | KMT2ASMN1; SMN2L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506177-B1 | PROCESS FOR THE PREPARATION OF THE ENANTIOMERIC FORMS OF 2-SUBSTITUTED 2-(2,5-DIOXOIMIDAZOLIDIN-1-YL)-ACETIC ACID DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-01-16 | — | — | EP | disclosed |
| US-6908752-B2 | Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1yl) -acetic acid derivatives | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-21 | — | — | US | disclosed |
| US-20030054507-A1 | Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1-yl) -acetic acid derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2003-03-20 | — | — | US | disclosed |