Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13440539 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL3606590 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL13441119 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL13440773 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL13440579 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL3600700 | 0.88 | KMT2A (0.52) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL3600696 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL13440778 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL13441023 | 0.85 | KMT2A (0.49) | ALDH1A1KMT2APOLBMEN1TSHR | |
| SCHEMBL13440780 | 0.84 | KMT2A (0.56) | ALDH1A1KMT2APOLBMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008127274-A2 | HETEROCYCLIC INHIBITORS OF BACTERIAL PEPTIDYL TRNA HYDROLASE AND USES THEREOF | PTC THERAPEUTICS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |