SCHEMBL459707

SCHEMBL459707

O=C1CCOC(=O)C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12158574 0.90 ALDH1A1 (0.46)
SCHEMBL12883403 0.81 CA1 (0.64)
SCHEMBL13317130 0.78 CA1 (0.58)
SCHEMBL1309086 0.77
SCHEMBL85837 0.74
SCHEMBL20676746 0.74 CA1 (0.48)
SCHEMBL181525 0.74
SCHEMBL12158580 0.74 LMNA (0.50)
SCHEMBL13324555 0.74 TSHR (0.85)
SCHEMBL19638419 0.74 TSHR (0.85)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3830160-B1 METHODS FOR REDUCING ALDEHYDE EMISSIONS IN POLYURETHANE FOAMS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-25 EP claimed
US-7094912-B2 Process for the preparation of 4-oxytetrahydropyran-2-ones KRKA, TOVARNA ZDRAVIL, D. D. (SI) 2006-08-22 US claimed
US-20050182263-A1 Proces for the preparation of 4-oxytetrahydropyran-2-ones KRKA, TOVARNA ZDRAVIL, D.D. (SI) 2005-08-18 US claimed
EP-1487814-B1 PROCESS FOR THE PREPARATION OF 4-OXYTETRAHYDROPYRAN-2-ONES KRKA TOVARNA ZDRAVIL D D NOVO (SI) 2005-08-10 EP claimed
EP-1487814-A1 PROCESS FOR THE PREPARATION OF 4-OXYTETRAHYDROPYRAN-2-ONES Krka Tovarna Zdravil, D.D., Novo Mesto (SI) 2004-12-22 EP claimed
WO-2003080591-A1 PROCESS FOR THE PREPARATION OF 4-OXYTETRAHYDROPYRAN-2-ONES KRKA TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) 2003-10-02 WO claimed
US-20020058822-A1 Process for making (2S, 3S, 5S) oxetanone derivatives MULLINS JOHN JASON GENTRY (US) 2002-05-16 US claimed
WO-2002032850-A1 PROCESS FOR MAKING (2S, 3S, 5S) OXETANONE DERIVATIVES MULLINS JOHN JASON GENTRY (US) 2002-04-25 WO claimed
US-20020045767-A1 PROCESS FOR MAKING (2S, 3S, 5S) OXETANONE DERIVATIVES BUSS, ROBERT P. 2002-04-18 US claimed
US-5389602-A PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1995-02-14 US claimed
EP-0345635-B1 Herbicidal tetrahydropyran-2,4-diones BASF AG (DE) 1994-10-05 EP claimed
EP-0325085-B1 HERBICIDAL DERIVATIVES OF TETRAHYDROPYRAN-2,4-DIONES BASF Aktiengesellschaft (DE) 1993-08-18 EP claimed
EP-0345635-A1 Herbicidal tetrahydropyran-2,4-diones BASF Aktiengesellschaft (DE) 1989-12-13 EP claimed
EP-0325085-A2 Herbicidal derivatives of tetrahydropyran-2,4-diones BASF Aktiengesellschaft (DE) 1989-07-26 EP claimed
US-4842638-A Herbicidal tetrahydro(thio)pyran-2,4-dione derivatives BASF AKTIENGESELLSCHAFT (DE) 1989-06-27 US claimed
US-4418142-A ALDEHYDE SCAVANGERS AGFA GEVAERT AKTIENGESELLSCHAFT (DE) 1983-11-29 US claimed
EP-0049449-B1 PHOTOSENSITIVE PHOTOGRAPHIC RECORDING MATERIAL BASED ON SILVER HALIDE Agfa-Gevaert AG (DE) 1983-09-28 EP claimed
EP-0049449-A1 Photosensitive photographic recording material based on silver halide Agfa-Gevaert AG (DE) 1982-04-14 EP claimed
JP-2085280-A None JP disclosed
EP-0049449-A1 Photosensitive photographic recording material based on silver halide Agfa-Gevaert AG (DE) 1982-04-14 EP disclosed