Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SOD1 | P00441 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597673 | 0.91 | SLC6A2 (0.39) | DRD2HTR1AKMT2AHTR2ASOD1 | |
| SCHEMBL4597120 | 0.82 | HRH3 (0.37) | DRD2HTR1AHTR2A | |
| SCHEMBL4163722 | 0.82 | CA1 (0.36) | — | |
| SCHEMBL4595444 | 0.80 | SIGMAR1 (0.46) | HTR7HTR2A | |
| SCHEMBL25845030 | 0.78 | CA1 (0.34) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL4172727 | 0.78 | CA1 (0.34) | — | |
| SCHEMBL4596810 | 0.78 | KCNH2 (0.46) | HTR2A | |
| SCHEMBL4595660 | 0.77 | KDM4E (0.42) | DRD2MEN1KMT2AADRA1AKDM4E | |
| SCHEMBL4597148 | 0.75 | LDHA (0.43) | DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9298888 | 0.74 | CA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874788-A1 | MONOSACCHARIDE DERIVATIVES AS ANTI-INFLAMMATORY AND/OR ANTI-CANCER AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111783-A1 | MONOSACCHARIDE DERIVATIVES AS ANTI-INFLAMMATORY AND/OR ANTI-CANCER AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-10-26 | — | — | WO | disclosed |