Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1430292 | 0.71 | — | — | |
| SCHEMBL377529 | 0.71 | — | — | |
| SCHEMBL2907727 | 0.60 | — | — | |
| SCHEMBL3221160 | 0.58 | — | — | |
| SCHEMBL14191718 | 0.55 | CHRNB2 (0.35) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL15001268 | 0.54 | ALDH1A1 (0.35) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL17743432 | 0.53 | — | — | |
| SCHEMBL17743459 | 0.53 | MC4R (0.36) | CHRNB2CHRNA7CHRNA4 | |
| Potassium Ion SCHEMBL11889137 | 0.53 | — | — | |
| Acetic Acid SCHEMBL25296519 | 0.53 | CHRNB2 (0.34) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907374-A2 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007012479-A2 | BENZYLPIPERAZINE DERIVATES AND THEIR MEDICAL USE | GLAXO GROUP LIMITED (GB) | 2007-02-01 | — | — | WO | disclosed |