SCHEMBL4597257

SCHEMBL4597257

C=C(C)C(=O)OC(=O)c1cccc(C(=O)O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA6 P23280 1/20 0.43
CA9 Q16790 1/20 0.43
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
AKR1C3 P42330 1/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
TP53 P04637 1/20 0.41
KMO O15229 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27706830 0.87 LOXL2 (0.49) CA12CA1CA2CA9POLB
Isophthalic Acid SCHEMBL9008990 0.86 CA12 (0.46) CA12CA1CA2CA6CA9
SCHEMBL17892405 0.86 CA12 (0.46) CA12CA1CA2CA6CA9
SCHEMBL9008994 0.86 CA12 (0.46) CA12CA1CA2CA6CA9
Benzoic Acid SCHEMBL27830619 0.85 ELANE (0.49) ELANEPOLBAPEX1HTTTDP1
SCHEMBL777588 0.84 ELANE (0.54) ELANEPOLBTDP1LMNAGAA
SCHEMBL28514832 0.84 ELANE (0.54) ELANEPOLBTDP1LMNAGAA
SCHEMBL3788226 0.82 ELANE (0.53) ELANEPOLBTDP1LMNAGAA
SCHEMBL3972789 0.82 ELANE (0.53) ELANEPOLBTDP1LMNAGAA
SCHEMBL9247544 0.82 GAA (0.50) CA12CA1CA2CA6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699953-B2 A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE SEED CO., LTD. (JP) 2004-03-02 US claimed
US-20030130461-A1 Lens made f synthetic resin and process for producing the same SEED CO., LTD. (JP) 2003-07-10 US claimed
EP-1316820-A1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME Seed Co., Ltd. (JP) 2003-06-04 EP claimed
EP-1316820-B1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME SEED CO LTD (JP) 2008-01-16 EP disclosed
US-6699953-B2 A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE SEED CO., LTD. (JP) 2004-03-02 US disclosed
US-20030130461-A1 Lens made f synthetic resin and process for producing the same SEED CO., LTD. (JP) 2003-07-10 US disclosed
EP-1316820-A1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME Seed Co., Ltd. (JP) 2003-06-04 EP disclosed