Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497291 | 0.91 | TSHR (0.34) | TSHRCYP3A4ATMTDP1 | |
| SCHEMBL7778333 | 0.86 | TSHR (0.37) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL8956031 | 0.86 | TSHR (0.35) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL7779129 | 0.85 | TSHR (0.33) | TSHRCYP3A4ATMTDP1 | |
| SCHEMBL1596232 | 0.83 | TSHR (0.46) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL7778318 | 0.82 | TSHR (0.31) | TSHR | |
| SCHEMBL7776909 | 0.82 | TSHR (0.33) | TSHRCYP3A4ATMTDP1 | |
| SCHEMBL11895465 | 0.82 | TSHR (0.45) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL4239989 | 0.81 | TSHR (0.59) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL481538 | 0.79 | TSHR (0.57) | TSHRCYP3A4ATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699953-B2 | A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE | SEED CO., LTD. (JP) | 2004-03-02 | — | — | US | claimed |
| US-20030130461-A1 | Lens made f synthetic resin and process for producing the same | SEED CO., LTD. (JP) | 2003-07-10 | — | — | US | claimed |
| EP-1316820-A1 | LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME | Seed Co., Ltd. (JP) | 2003-06-04 | — | — | EP | claimed |
| EP-0690080-A2 | Hindered-hydroxyl functional (meth) acrylate monomers containing di (meth) acrylates and compositions including same | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-01-03 | — | — | EP | claimed |
| US-5442023-A | Without premature crosslinking or gel formation; curable protective coatings, inks, adhesives | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-08-15 | — | — | US | claimed |
| EP-1316820-B1 | LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME | SEED CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-6699953-B2 | A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE | SEED CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20030130461-A1 | Lens made f synthetic resin and process for producing the same | SEED CO., LTD. (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1316820-A1 | LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME | Seed Co., Ltd. (JP) | 2003-06-04 | — | — | EP | disclosed |
| EP-0690080-A2 | Hindered-hydroxyl functional (meth) acrylate monomers containing di (meth) acrylates and compositions including same | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5442023-A | Without premature crosslinking or gel formation; curable protective coatings, inks, adhesives | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |