SCHEMBL481538

SCHEMBL481538

C=C(C)C(=O)OCC(CC)CO

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.57
THRB P10828 1/20 0.44
ALDH1A1 P00352 5/20 0.38
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ATM Q13315 1/20 0.36
CA2 P00918 1/20 0.32
TGFBR1 P36897 1/20 0.32
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2442706 0.91 TSHR (0.52) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL3974700 0.90 TSHR (0.63) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL75001 0.90 TSHR (0.63) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL65970 0.90 TSHR (0.63) TSHRTHRBALDH1A1TDP1TGFBR1
SCHEMBL3685216 0.90 TSHR (0.63) TSHRTHRBALDH1A1TDP1TGFBR1
SCHEMBL497290 0.86 TSHR (0.59) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL7778330 0.85 TSHR (0.46) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL5879358 0.85 TSHR (0.53) TSHRTHRBALDH1A1CYP3A4TDP1
Methacrylic Acid SCHEMBL20574597 0.85 TSHR (0.57) TSHRTHRBALDH1A1CYP3A4TDP1
SCHEMBL7779126 0.84 TSHR (0.53) TSHRTHRBALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11992538-B2 Polymerizable dental composition based on condensed silanes VOCO GMBH (DE) 2024-05-28 US claimed
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES VOCO GMBH (DE) 2021-02-25 US claimed
US-8901192-B2 (Meth)acrylic resin composition DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2014-12-02 US claimed
US-20120205043-A1 (METH)ACRYLIC RESIN COMPOSITION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-08-16 US claimed
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP claimed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP claimed
EP-0690080-A2 Hindered-hydroxyl functional (meth) acrylate monomers containing di (meth) acrylates and compositions including same UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-01-03 EP claimed
EP-0675141-A1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-10-04 EP claimed
US-5442023-A Without premature crosslinking or gel formation; curable protective coatings, inks, adhesives UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-08-15 US claimed
US-5420341-A Acrylic ester polymers UNION CARBIDE CHEMICALS & PLASTICS (US) 1995-05-30 US claimed
US-5412049-A Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-05-02 US claimed
WO-1994009077-A1 PROCESS OF FORMING A LIQUID MIXTURE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-28 WO claimed
EP-0594109-A1 Hindered-hydroxyl functional (meth)acrylate esters, copolymers containing them and compositions including same UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-27 EP claimed
US-5290602-A Polymer of hydroxyalkyl Umetheacrylate and compressed fluid UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-03-01 US claimed
EP-4400223-A1 DIGITAL EMBOSSING CREATION METHOD Sakata INX Corporation (JP) 2024-07-17 EP disclosed
US-12017402-B2 Method for forming anti-glare hard coat layer NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) 2024-06-25 US disclosed
EP-4365250-A1 MIGRATION-PREVENTING COATING AGENT Sakata INX Corporation (JP) 2024-05-08 EP disclosed
WO-1994009077-A1 PROCESS OF FORMING A LIQUID MIXTURE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-28 WO disclosed
EP-0594109-A1 Hindered-hydroxyl functional (meth)acrylate esters, copolymers containing them and compositions including same UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-04-27 EP disclosed
US-5290602-A Polymer of hydroxyalkyl Umetheacrylate and compressed fluid UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1994-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11992538-B2 Polymerizable dental composition based on condensed silanes NCAPH, RCC1, NCAPD2 TSHR 4596/4885THRB 4522/4885ALDH1A1 1481/4885
US-20210052469-A1 POLYMERIZABLE DENTAL COMPOSITION BASED ON CONDENSED SILANES NCAPH, RCC1, NCAPD2 TSHR 4596/4885THRB 4522/4885ALDH1A1 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.