Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118354 | 0.85 | GAA (0.48) | SMN1; SMN2GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL13875983 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL3716249 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL385247 | 0.80 | KDM4E (0.62) | SMN1; SMN2GAAL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL1287025 | 0.79 | KDM5C (0.51) | SMN1; SMN2ALDH1A1KDM4EEIF2AK2PIK3CA | |
| SCHEMBL63569 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL23195583 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2GAAALDH1A1KDM4ETSHR | |
| SCHEMBL8190316 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL3930162 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2GAAALDH1A1KDM4EMAPT | |
| SCHEMBL3398936 | 0.78 | SIGMAR1 (0.48) | ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122242-B1 | CYANOPHENYL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | disclosed |
| US-6673799-B1 | INHIBITS BINDING TO ANDROGEN RECEPTOR; ANTIANDROGEN | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2004-01-06 | — | — | US | disclosed |
| EP-1122242-A1 | CYANOPHENYL DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | SMN1; SMN2 4733/4885GAA 4258/4885L3MBTL1 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.