Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 known ✓ | P30542 | 3/20 | 0.89 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 3/20 | 0.89 |
| ▸ | ADORA2A known ✓ | P29274 | 1/20 | 0.89 |
| ▸ | ADORA2B known ✓ | P29275 | 1/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.89 |
| ▸ | DPP4 | P27487 | 1/20 | 0.89 |
| ▸ | MEN1 | O00255 | 1/20 | 0.89 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.89 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.89 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.89 |
| ▸ | GAPDH | P04406 | 1/20 | 0.89 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.89 |
| ▸ | STAT6 | P42226 | 1/20 | 0.89 |
| ▸ | PI4KA | P42356 | 1/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.89 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.89 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.89 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.89 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.89 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL6242700 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL9171507 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL3046213 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL3031964 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL1746637 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL50788 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL468212 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL1744578 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Vidarabine SCHEMBL7103173 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL9147194 | 1.00 | ADORA1 (0.89) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4600370-A1 | NUDE.1 AS A DECAPPING ENZYME FOR COFACTOR- AND \"CANONICALLY\"-CAPPED RNA SPECIES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-08-13 | — | — | EP | claimed |
| US-20250049894-A1 | TREATMENT OF NUDT2 MUTATION | UNIV GENEVE (CH) | 2025-02-13 | — | — | US | claimed |
| EP-4408431-A1 | TREATMENT OF NUDT2 MUTATION | Université de Genève (CH) | 2024-08-07 | — | — | EP | claimed |
| EP-4389214-A2 | USE OF TRIMETHOXYBENZYL ACETYLSINAPATE, ADVANTAGEOUSLY IN COMBINATION WITH AT LEAST ONE SUNSCREEN, FOR PROTECTING THE SKIN | Thorel, Jean-Noël (FR) | 2024-06-26 | — | — | EP | claimed |
| EP-3466419-B1 | USE OF TRIMETHOXYBENZYL ACETYLSINAPATE, ADVANTAGEOUSLY IN COMBINATION WITH AT LEAST ONE SUNSCREEN, FOR PROTECTING THE SKIN | THOREL JEAN NOEL (FR) | 2024-05-08 | — | — | EP | claimed |
| CN-117070547-A | Application of modified APaH gene in improving expression activity of exogenous gene | 齐鲁工业大学(山东省科学院) | 2023-11-17 | — | — | CN | claimed |
| WO-2023052411-A1 | TREATMENT OF NUDT2 MUTATION | UNIVERSITÉ DE GENÈVE (CH) | 2023-04-06 | — | — | WO | claimed |
| EP-3466419-A1 | USE OF TRIMETHOXYBENZYL ACETYLSINAPATE, ADVANTAGEOUSLY IN COMBINATION WITH AT LEAST ONE SUNSCREEN, FOR PROTECTING THE SKIN | Thorel, Jean-Noël (FR) | 2019-04-10 | — | — | EP | claimed |
| EP-1581177-B1 | CUTANEOUS METABOLIC BIO-ACTIVATOR | THOREL JEAN NOEL (FR) | 2018-04-11 | — | — | EP | claimed |
| US-20150369817-A1 | PLATELET BIOMARKERS IN CANCER DIAGNOSIS | NEOPROTEOMICS AB (SE) | 2015-12-24 | — | — | US | claimed |
| EP-0969848-A1 | USE OF DIADENOSINE POLYPHOSPHATES FOR REDUCING BLOOD PRESSURE | Clemson University (US) | 2000-01-12 | — | — | EP | claimed |
| WO-1999043326-A1 | USE OF A CARDIAC PURINOCEPTOR TO EFFECT CELLULAR GLUCOSE UPTAKE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1999-09-02 | — | — | WO | claimed |
| EP-0721955-B1 | Diadenosine tetraphosphate tetrasodium salt dodecahydrate crystals | UNITIKA LTD (JP) | 1999-04-07 | — | — | EP | claimed |
| WO-1998030222-A1 | USE OF DIADENOSINE POLYPHOSPHATES FOR REDUCING BLOOD PRESSURE | CLEMSON UNIVERSITY (US) | 1998-07-16 | — | — | WO | claimed |
| EP-0566140-B1 | Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof | UNITIKA LTD (JP) | 1998-07-01 | — | — | EP | claimed |
| US-5306629-A | Two-stage reaction using two enzymes: adenosine-5-triphosphate sulfurylase and diadenosine tetraphosphate phosphorylase as catalysts, and adenosine-5-triphosphate, polyphosphate and a sulfate as substrates | UNITIKA LTD. (JP) | 1994-04-26 | — | — | US | claimed |
| EP-0566140-A2 | Method for producing dinucleoside polyphosphate, nucleoside polyphosphate or derivatives thereof | UNITIKA LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0247819-B1 | PROCESS FOR PRODUCING DIADENOSINE TETRAPHOSPHATE AND DERIVATIVES THEREOF | UNITIKA LTD. (JP) | 1991-07-24 | — | — | EP | claimed |
| US-4886749-A | Process for producing diadenosine tetraphosphate and derivatives thereof | UNITIKA LTD. (JP) | 1989-12-12 | — | — | US | claimed |
| EP-0247819-A2 | Process for producing diadenosine tetraphosphate and derivatives thereof | UNITIKA LTD. (JP) | 1987-12-02 | — | — | EP | claimed |