Adenosine

Adenosine

SCHEMBL50788

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O=P(O)(O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3

The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 known ✓ P30542 3/20 0.89
ADORA3 known ✓ P0DMS8 3/20 0.89
ADORA2A known ✓ P29274 1/20 0.89
ADORA2B known ✓ P29275 1/20 0.89
SMN1; SMN2 Q16637 3/20 0.89
DPP4 P27487 1/20 0.89
MEN1 O00255 1/20 0.89
SLC28A1 O00337 1/20 0.89
MAP3K7 O43318 1/20 0.89
SLC28A2 O43868 1/20 0.89
GAPDH P04406 1/20 0.89
MAPK1 P28482 1/20 0.89
STAT6 P42226 1/20 0.89
PI4KA P42356 1/20 0.89
KMT2A Q03164 1/20 0.89
PI4K2B Q8TCG2 1/20 0.89
DOT1L Q8TEK3 1/20 0.89
SLC29A1 Q99808 1/20 0.89
PI4K2A Q9BTU6 1/20 0.89
SLC28A3 Q9HAS3 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine SCHEMBL6242700 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL9171507 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL3046213 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL459769 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL3031964 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL1746637 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL468212 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL1744578 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Vidarabine SCHEMBL7103173 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL9147194 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 17365 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144821-A1 Treatment of Blood Transfusion-Dependent Patients with Hematologic Malignancies HEMANEXT INC. (US) 2026-05-28 US claimed
US-20260144822-A1 Treatment of Burn Patients with Hypoxic Blood HEMANEXT INC. (US) 2026-05-28 US claimed
CN-122075514-A Use of glycogen phosphatase B agonists for the treatment of neurodegenerative diseases 2026-05-26 CN claimed
CN-122072262-A Detection method and kit for absolute quantification of multiple neurotransmitters and related metabolites 清华大学 2026-05-22 CN claimed
WO-2026102307-A1 ACELLULAR BLOOD ALTERNATIVE FOR TRANSFUSION AND ORGAN PERFUSION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-15 WO claimed
EP-4741012-A2 COMPOSITIONS AND METHODS FOR REDUCING AMYLOID BETA FORMATION AND COMPOSITION THEREFORE Aribio Co., Ltd. (KR) 2026-05-13 EP claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260125717-A1 Bioreactor and Process for Forming Polyhydroxybutyrate Directly from Depolymerized Polyhydroxybutyrate KIMBERLY CLARK CO (US) 2026-05-07 US claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US claimed
WO-2026085618-A1 METHOD OF IMMOBILIZING CAPTURE PROBES TO SOLID PHASES FOR TARGET SUBSTANCE DETECTION YYZ PHARMATECH INC. (CA) 2026-04-30 WO claimed
US-4277562-A Stabilized liquid enzyme and coenzyme compositions MEDICAL ANALYSIS SYSTEMS, INC. 1981-07-07 US claimed
US-4271264-A Stabilized liquid enzyme and coenzyme compositions MEDICAL ANALYSIS SYSTEMS, INC. 1981-06-02 US claimed
US-4250254-A USING AN AQUEOUS VEHICLE, A MISCIBLE POLYOL SOLVENT, AND A POLYMER; PH; SHELF LIFE; MEDICAL DIAGNOSIS MEDICAL ANALYSIS SYSTEMS, INC. 1981-02-10 US claimed
US-4209316-A NUCLEOSIDES OR NUCLEOTIDES WITH A BUFFER UNIVERSITY PATENTS, INC. (US) 1980-06-24 US claimed
US-4199498-A Macromolecularized adenine derivatives SNAMPROGETTI S.P.A. (IT) 1980-04-22 US claimed
EP-0006582-A2 Method for stabilizing solutions of gamma-glutamyl-p-nitroanilide Modrovich, Ivan Endre (US) 1980-01-09 EP claimed
US-4164444-A Method for preparing adenosine triphosphate MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1979-08-14 US claimed
US-4071413-A Method for determining free fatty acids in blood serum using fatty acid activating enzymes ONO PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US claimed
US-4061828-A Modified, grafted mineral carriers RHONE-POULENC INDUSTRIES (FR) 1977-12-06 US claimed
US-4017597-A STORAGE STABILITY, MEDICAL DIAGNOSIS MONSANTO COMPANY (US) 1977-04-12 US claimed