Adenosine

Adenosine

SCHEMBL468212

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3

The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 known ✓ P30542 3/20 0.89
ADORA3 known ✓ P0DMS8 3/20 0.89
ADORA2A known ✓ P29274 1/20 0.89
ADORA2B known ✓ P29275 1/20 0.89
SMN1; SMN2 Q16637 3/20 0.89
DPP4 P27487 1/20 0.89
MEN1 O00255 1/20 0.89
SLC28A1 O00337 1/20 0.89
MAP3K7 O43318 1/20 0.89
SLC28A2 O43868 1/20 0.89
GAPDH P04406 1/20 0.89
MAPK1 P28482 1/20 0.89
STAT6 P42226 1/20 0.89
PI4KA P42356 1/20 0.89
KMT2A Q03164 1/20 0.89
PI4K2B Q8TCG2 1/20 0.89
DOT1L Q8TEK3 1/20 0.89
SLC29A1 Q99808 1/20 0.89
PI4K2A Q9BTU6 1/20 0.89
SLC28A3 Q9HAS3 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine SCHEMBL6242700 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL9171507 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL3046213 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL459769 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL3031964 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL1746637 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL50788 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL1744578 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Vidarabine SCHEMBL7103173 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1
Adenosine SCHEMBL9147194 1.00 ADORA1 (0.89) ADORA1SMN1; SMN2ADORA3DPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 775 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605523-A1 OLIGONUCLEOTIDES AND METHODS FOR CAPTURING SINGLE-STRANDED TEMPLATES AND/OR TEMPLATES WITH 3' OVERHANGS Foundation Medicine, Inc. (US) 2025-08-27 EP claimed
WO-2024137316-A1 OLIGONUCLEOTIDES AND METHODS FOR CAPTURING SINGLE-STRANDED TEMPLATES AND/OR TEMPLATES WITH 3' OVERHANGS FOUNDATION MEDICINE, INC. (US) 2024-06-27 WO claimed
US-11964149-B2 Facial beautifying and care apparatus BIBOTING INTERNATIONAL CO., LTD. (TW) 2024-04-23 US claimed
US-20230225928-A1 FACIAL BEAUTIFYING AND CARE APPARATUS LIU PO CHANG (TW) 2023-07-20 US claimed
EP-4153322-A1 COUPLED TERPENE CONJUGATE Laboratoires Eriger (FR) 2023-03-29 EP claimed
WO-2022155751-A1 PRENYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2022-07-28 WO claimed
US-20220032050-A1 FACIAL BEAUTIFYING AND CARE APPARATUS LIU, PO-CHANG (TW) 2022-02-03 US claimed
CN-108753808-A A kind of recombinant expression carrier, recombinant expression host and its method for synthesizing adenosine triphosphoric acid 浙江海正药业股份有限公司 2018-11-06 CN claimed
US-9193990-B2 Bioluminescent metal ion assay Thompson, Richard B. (US) 2015-11-24 US claimed
US-20140273038-A1 BIOLUMINESCENT METAL ION ASSAY Thompson, Richard B. (US) 2014-09-18 US claimed
US-20050009847-A1 Compounds and methods for increasing neurogenesis NEURONOVA AB (COMPANY REGISTRATION NO. 556703-0118) (SE) 2005-01-13 US claimed
WO-2004045592-A2 COMPOUNDS AND METHODS FOR INCREASING NEUROGENESIS NEURONOVA AB (SE) 2004-06-03 WO claimed
CN-1382699-A Polypeptide-nuclear triphosphoddenosine bindin-30.47 and polynucleotide for coding it BIOWINDOW GENE DEV INC (CN) 2002-12-04 CN claimed
EP-0344807-B1 Method for evaluating the permeability of a thin membrane HAMAMATSU PHOTONICS KK (JP) 1997-09-03 EP claimed
US-5059526-A Storage stability, accuracy KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1991-10-22 US claimed
EP-0344807-A2 Method for evaluating the permeability of a thin membrane HAMAMATSU PHOTONICS K.K. (JP) 1989-12-06 EP claimed
US-4833075-A Immobilized luciferase for the quantitative determination of ATP CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1989-05-23 US claimed
US-4698387-A Allosteric conjugates of hemoglobin and use as blood substitutes INTERMEDICAT GMBH (CH) 1987-10-06 US claimed
EP-0145373-A2 Purification of cancer-associated protein and preparation of antibody thereto THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1985-06-19 EP claimed
WO-1985002467-A1 PURIFICATION OF CANCER-ASSOCIATED PROTEIN AND PREPARATION OF ANTIBODY THERETO THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1985-06-06 WO claimed