Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249039 | 0.98 | HSD11B1 (0.31) | HSD11B1DPP4 | |
| SCHEMBL27968867 | 0.96 | DPP4 (0.32) | DPP4 | |
| SCHEMBL28426928 | 0.83 | HTT (0.34) | HSD11B1RAB9AADH1CADH1ATSHR | |
| SCHEMBL27825152 | 0.83 | TSHR (0.38) | HSD11B1RAB9AADH1CADH1ATSHR | |
| SCHEMBL27687060 | 0.81 | TSHR (0.36) | HSD11B1RAB9ATSHR | |
| SCHEMBL28897617 | 0.79 | RAB9A (0.33) | HSD11B1RAB9AADH1CADH1AALDH1A1 | |
| SCHEMBL27786904 | 0.79 | MEN1 (0.33) | HSD11B1RAB9AADH1CADH1ATSHR | |
| SCHEMBL28318717 | 0.79 | TSHR (0.33) | RAB9ATSHR | |
| SCHEMBL28415860 | 0.76 | RAB9A (0.32) | HSD11B1RAB9ATSHR | |
| SCHEMBL28169430 | 0.74 | PHGDH (0.40) | HSD11B1ADH1CADH1ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968345-B | 1, 5-naphthyridine derivatives and ME L K inhibitors containing 1, 5-naphthyridine derivatives | 肿瘤疗法科学股份有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-105531273-A | Bromodomain inhibitors | ABBVIE INC | 2016-04-27 | — | — | CN | disclosed |
| CN-105518007-A | BROMODOMAIN INHIBITORS | ABBVIE INC | 2016-04-20 | — | — | CN | disclosed |
| CN-105143206-A | Pyrimidine-2,4-diamine derivatives for treatment of cancer | THOMAS HELLEDAYS STIFTELSE F R MEDICINSK FORSKNING | 2015-12-09 | — | — | CN | disclosed |
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |