Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698466 | 0.91 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL3696133 | 0.87 | PARP10 (0.67) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL31621360 | 0.85 | ALDH1A1 (0.81) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL4596521 | 0.84 | KDM4E (0.65) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL31556429 | 0.82 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL510519 | 0.82 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL8016831 | 0.82 | KDM4E (0.66) | ALDH1A1L3MBTL1KDM4EPOLBNPC1 | |
| SCHEMBL4597726 | 0.81 | KDM4E (0.60) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL3692143 | 0.81 | PARP10 (0.67) | ALDH1A1L3MBTL1KDM4EOPRM1OPRD1 | |
| SCHEMBL1448984 | 0.80 | ALDH1A1 (0.76) | ALDH1A1KDM4EPARP10PARP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |