Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.76 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.70 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.70 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11068404 | 0.87 | ALDH1A1 (1.00) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| SCHEMBL63361 | 0.87 | ALDH1A1 (1.00) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| SCHEMBL20024752 | 0.86 | PARP10 (0.58) | ALDH1A1PARP10PARP3PARP15SRD5A2 | |
| SCHEMBL20032247 | 0.86 | PARP10 (0.62) | ALDH1A1PARP10PARP3PARP15SRD5A2 | |
| SCHEMBL8161786 | 0.85 | ALDH1A1 (0.95) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| SCHEMBL8594185 | 0.85 | ALDH1A1 (0.95) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| SCHEMBL28234323 | 0.85 | ALDH1A1 (0.95) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| SCHEMBL29693000 | 0.85 | ALDH1A1 (0.95) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| Hydrochloric Acid SCHEMBL740726 | 0.85 | ALDH1A1 (0.95) | ALDH1A1PARP10PARP3SRD5A2CA1 | |
| SCHEMBL28508718 | 0.85 | ALDH1A1 (0.95) | ALDH1A1PARP10PARP3SRD5A2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4314004-B1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | LILLY CO ELI (US) | 2025-01-22 | — | — | EP | disclosed |
| US-12162905-B2 | Carboxy substituted glucocorticoid receptor agonists | ELI LILLY AND COMPANY (US) | 2024-12-10 | — | — | US | disclosed |
| EP-4314004-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-116888137-A | Carboxy substituted glucocorticoid receptor agonists | 伊莱利利公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230227493-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2023-07-20 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20220306681-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2022-09-29 | — | — | US | disclosed |
| WO-2022204099-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2022-09-29 | — | — | WO | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-10655029-B2 | Inkjet ink and coloring composition | RICOH COMPANY, LTD. (JP) | 2020-05-19 | — | — | US | disclosed |
| US-20050215557-A1 | Triazaspiro[5.5]undecane derivative and pharmaceutical composition comprising the same as active ingredient | ONO PHARMACEUTICAL CO., LTD. | 2005-09-29 | — | — | US | disclosed |
| EP-1541573-A1 | NOVEL CRYSTALS OF TRIAZASPIRO 5.5 UNDECANE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1541574-A1 | TRIAZASPIRO 5.5 UNDECANE DERIVATIVES AND DRUGS COMPRISI NG THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-20040106619-A1 | Drugs containing triazaspiro[5.5]undecane derivatives as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| US-20040082584-A1 | Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1378509-A1 | DRUGS CONTAINING TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-07 | — | — | EP | disclosed |
| EP-1378510-A1 | TRIAZASPIRO 5.5]UNDECANE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-01-07 | — | — | EP | disclosed |
| EP-1304924-A2 | COMPOSITIONS FOR REPELLING CRAWLING INSECTS | Bayer Aktiengesellschaft (DE) | 2003-05-02 | — | — | EP | disclosed |
| US-20020094993-A1 | Compositions for repelling crawling insects | S.C. JOHNSON & SON, INC. | 2002-07-18 | — | — | US | disclosed |
| WO-2002005646-A2 | COMPOSITIONS FOR REPELLING CRAWLING INSECTS | S.C. JOHNSON & SON, INC. (US) (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106619-A1 | Drugs containing triazaspiro[5.5]undecane derivatives as the active ingredient | NONO, NAA15, USO1 | ALDH1A1 1704/4885PARP10 1842/4885PARP3 3085/4885 |
| US-20230227493-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, MC2R, NR3C2 | ALDH1A1 2971/4885PARP10 3159/4885PARP3 4146/4885 |
| US-20040082584-A1 | Triazaspiro[5.5]undecane derivatives and drugs containing the same as the active ingredient | ACKR3, CXCR5, CCL11 | ALDH1A1 809/4885PARP10 2068/4885PARP3 2468/4885 |
| US-20220306681-A1 | CARBOXY SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS | NR3C1, MC2R, NR3C2 | ALDH1A1 2971/4885PARP10 3159/4885PARP3 4146/4885 |
| US-20050215557-A1 | Triazaspiro[5.5]undecane derivative and pharmaceutical composition comprising the same as active ingredient | ACKR3, CCL11, CCR7 | ALDH1A1 861/4885PARP10 1939/4885PARP3 2399/4885 |
| US-20020094993-A1 | Compositions for repelling crawling insects | ACHE, DDT, GAP43 | ALDH1A1 1488/4885PARP10 4718/4885PARP3 4620/4885 |
| US-12162905-B2 | Carboxy substituted glucocorticoid receptor agonists | NR3C1, MC2R, NR3C2 | ALDH1A1 2971/4885PARP10 3159/4885PARP3 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.