Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597909 | 1.00 | CCR5 (0.45) | CCR5 | |
| SCHEMBL5575457 | 0.89 | GPR119 (0.45) | CCR5 | |
| SCHEMBL5576732 | 0.89 | GPR119 (0.45) | CCR5 | |
| SCHEMBL5576730 | 0.89 | GPR119 (0.45) | CCR5 | |
| SCHEMBL5575448 | 0.89 | GPR119 (0.45) | CCR5 | |
| SCHEMBL5572451 | 0.79 | STS (0.43) | CCR5 | |
| SCHEMBL5576710 | 0.75 | CCR5 (0.70) | CCR5 | |
| SCHEMBL5576550 | 0.75 | CCR5 (0.70) | CCR5 | |
| SCHEMBL5576721 | 0.75 | CCR5 (0.70) | CCR5 | |
| SCHEMBL5576531 | 0.75 | CCR5 (0.70) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |