Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.51 |
| ▸ | TPH1 | P17752 | 6/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | GRB2 | P62993 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003025 | 1.00 | SLC7A5 (0.51) | SLC7A5TPH1PTPN1PTGS1ITGB3 | |
| SCHEMBL4596794 | 0.99 | TPH1 (0.50) | SLC7A5TPH1PTPN1PTGS1ITGB3 | |
| Hydrochloric Acid SCHEMBL4597708 | 0.99 | TPH1 (0.50) | SLC7A5TPH1PTPN1PTGS1ITGB3 | |
| SCHEMBL4828572 | 0.89 | HDAC6 (0.49) | TPH1HDAC3HDAC6NCOR2EPHX2 | |
| SCHEMBL4597924 | 0.87 | HDAC8 (0.53) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL4597882 | 0.87 | HDAC8 (0.64) | SLC7A5TPH1PTPN1PTGS1ITGB3 | |
| SCHEMBL14003044 | 0.84 | HDAC6 (0.47) | HDAC3HDAC6NCOR2EPHX2PPARG | |
| SCHEMBL14002998 | 0.83 | SMN1; SMN2 (0.51) | TPH1HDAC6EPHX2PPARGPPARA | |
| Hydrochloric Acid SCHEMBL4598799 | 0.83 | HDAC6 (0.46) | HDAC3HDAC6NCOR2EPHX2PPARG | |
| SCHEMBL4598163 | 0.83 | HDAC6 (0.44) | HDAC3HDAC6NCOR2EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7456292-B2 | Hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. (US) | 2008-11-25 | — | — | US | claimed |
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | claimed |
| EP-1906731-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | Bexel Pharmaceuticals Inc (US) | 2008-04-09 | — | — | EP | claimed |
| WO-2007005603-A2 | NOVEL HYDROXAMIC ACID-CONTAINING AMINO ACID DERIVATIVES | BEXEL PHARMACEUTICALS, INC. (US) | 2007-01-11 | — | — | WO | claimed |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | claimed |
| US-7456292-B2 | Hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | disclosed |
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | BEXEL PHARMACEUTICALS. INC. | 2008-08-21 | — | — | US | disclosed |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | BEXEL PHARMACEUTICALS, INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200521-A1 | Novel hydroxamic acid containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | SLC7A5 51/4885TPH1 583/4885PTPN1 2671/4885 |
| US-20070004776-A1 | Novel hydroxamic acid-containing amino acid derivatives | HGFAC, HCAR2, BCAT1 | SLC7A5 79/4885TPH1 531/4885PTPN1 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.