Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.54 |
| ▸ | CTSS | P25774 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4981744 | 0.83 | CTSS (0.56) | CTSKCTSSATMPPARG | |
| SCHEMBL27601240 | 0.83 | CTSS (0.56) | CTSKCTSSATMPPARG | |
| SCHEMBL4981754 | 0.83 | CTSS (0.56) | CTSKCTSSATMPPARG | |
| SCHEMBL8351861 | 0.82 | CTSK (0.60) | CTSKCTSSOPRK1MAPTATM | |
| SCHEMBL2376080 | 0.81 | CTSS (0.56) | CTSKCTSSATMPPARG | |
| SCHEMBL2376072 | 0.81 | CTSS (0.56) | CTSKCTSSATMPPARG | |
| SCHEMBL90836 | 0.81 | CTSK (0.56) | CTSKCTSSOPRK1MAPTATM | |
| SCHEMBL16847362 | 0.81 | CTSK (0.56) | CTSKCTSSOPRK1MAPTATM | |
| SCHEMBL5873385 | 0.79 | CTSK (0.60) | CTSKCTSSOPRK1MAPTATM | |
| SCHEMBL4788125 | 0.78 | TDP1 (0.59) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |