Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597860 | 0.85 | GAA (0.38) | SMN1; SMN2HPGDGAANPSR1MAPT | |
| SCHEMBL4596630 | 0.81 | CYP26A1 (0.40) | HPGDGAALMNAALDH1A1TP53 | |
| SCHEMBL4597190 | 0.80 | HAO1 (0.44) | MAPTLMNAALDH1A1POLB | |
| SCHEMBL4596529 | 0.79 | TYMS (0.44) | SMN1; SMN2HPGDGAALMNAALDH1A1 | |
| SCHEMBL5575510 | 0.78 | PTGDR2 (0.46) | NR4A1APEX1SMN1; SMN2PTGDR2ALOX15 | |
| SCHEMBL5576695 | 0.78 | ALOX15 (0.42) | SMN1; SMN2HPGDGAANPSR1ALOX15 | |
| SCHEMBL4597157 | 0.75 | ALDH1A1 (0.46) | SMN1; SMN2HPGDGAANPSR1ALOX15 | |
| SCHEMBL5575494 | 0.75 | NPC1 (0.37) | SMN1; SMN2HPGDMAPTALDH1A1TP53 | |
| SCHEMBL4596971 | 0.75 | CYP4F2 (0.41) | SMN1; SMN2HPGDGAAMAPTALDH1A1 | |
| SCHEMBL8619219 | 0.74 | ALOX15 (0.63) | NR4A1APEX1SMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |