Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 14/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4906078 | 0.93 | MAPKAPK2 (0.47) | QPCTMAPKAPK2KMT2APOLBMEN1 | |
| SCHEMBL4597016 | 0.93 | MAPKAPK2 (0.47) | QPCTMAPKAPK2KMT2APOLBMEN1 | |
| SCHEMBL4598170 | 0.81 | MAPKAPK2 (0.58) | QPCTMAPKAPK2KMT2APOLBMEN1 | |
| SCHEMBL4908999 | 0.81 | MAPKAPK2 (0.58) | QPCTMAPKAPK2KMT2APOLBMEN1 | |
| SCHEMBL4599129 | 0.81 | MAPKAPK2 (0.45) | QPCTMAPKAPK2 | |
| SCHEMBL4598655 | 0.77 | MAPKAPK2 (0.41) | QPCTMAPKAPK2KMT2APOLBMEN1 | |
| SCHEMBL4597296 | 0.74 | ROCK2 (0.52) | QPCTKMT2ACDK1MMP12NPC1 | |
| SCHEMBL4910847 | 0.73 | MAPKAPK2 (0.42) | QPCTMAPKAPK2KMT2APOLBMEN1 | |
| SCHEMBL4598622 | 0.73 | QPCT (0.50) | QPCTCDK1 | |
| SCHEMBL4598309 | 0.73 | MAPK1 (0.40) | QPCTMAPKAPK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910312-A1 | QUADRATIC ACID II DERIVATIVES | Merck Patent GmbH (DE) | 2008-04-16 | — | — | EP | claimed |
| WO-2007014608-A1 | QUADRATIC ACID II DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-02-08 | — | — | WO | claimed |