Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14870380 | 1.00 | CTSS (0.46) | CTSSCTSKGBA1HDAC4HDAC7 | |
| SCHEMBL21509870 | 0.86 | POLB (0.41) | CTSSCTSKSYKAAK1 | |
| SCHEMBL10448435 | 0.86 | POLB (0.41) | CTSSCTSKSYKAAK1 | |
| SCHEMBL16690871 | 0.85 | AAK1 (0.48) | CTSSCTSKGBA1SYKAAK1 | |
| SCHEMBL4597442 | 0.85 | CTSL (0.46) | CTSSCTSKSYKAAK1 | |
| SCHEMBL10319148 | 0.85 | CTSL (0.46) | CTSSCTSKSYKAAK1 | |
| SCHEMBL4597840 | 0.85 | CTSL (0.46) | CTSSCTSKSYKAAK1 | |
| SCHEMBL28076446 | 0.85 | AAK1 (0.48) | CTSSCTSKGBA1SYKAAK1 | |
| SCHEMBL970153 | 0.84 | CTSS (0.44) | CTSSCTSKSYKAAK1 | |
| SCHEMBL28763012 | 0.84 | CTSS (0.44) | CTSSCTSKSYKAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |